Research Project Level Inventory by Agents under study then Focal Areas
Study Types: Dioxins
Category: Human Health Effects(75)- Physiological effects of xenobiotic oestrogens in mammals
- Investigation of Biologically Active Compounds in Sewage Sludge and Sludge-Amended Agriculture Soils
- Endocrine modulators and the human female reproductive system
- Sex Hormones Effects On The Brain
- xenoestrogens and sperm quality in man
- Environment and male reproductive health
- Role of environmental enstrogens/antiestrogens in the development of prostatic discases
- Environmental oestrogens and oestrogenic molecules
- Evironmental halogenated aromatic hydrocarbons, mechanism of action, interactions and test-system development
- Hormone Disruptors in Food
- environmental pcb-exposure and developmental deficit: neurobehavioural functions beyond age 18 months until school age
- Interactions between phytoestrogens and other environmental estrogens with the novel estrogen receptor beta (ERb). Dioxin (Ah receptor)-ERb interactions.
- 01332-22 REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF DIOXIN
- 01884-20 HALOGENATED AROMATIC HYDROCARBONS
- 03561-11 DIOXIN/EPITHELIAL CELL INTERACTIONS--MECHANISM AND ASSAY
- 03606-12 ARACHIDONATE PRODUCTS IN DIOXIN AND PCB TOXICITY
- 03966-09 CYTOKINE ALTERATIONS IN TCDD IMMUNOTOXICITY
- 04869-10 REGULATION OF THE AH RECEPTOR
- 06272-05 AH RECEPTOR IN NONMAMMALIAN SPECIES
- 06273-05 MOLECULAR MECHANISMS OF DIOXIN ACTION
- 06807-01A1 MOLECULAR BASIS FOR TCDD MODULATION OF ESTROGEN AT OVARY
- 06811-03 AH RECEPTOR--TRANSGENIC MICE FOR RISK ASSESSMENT
- 06883-04 TRANSGENIC MODELS OF DIOXIN ACTION
- 07260-04 ORGANOCHLORINE COMPOUNDS AND HUMAN BREAST CYTOCHROME P450
- 07273-03 TIMING OF ENVIRONMENTAL CHEMICALS IN BREAST CANCER
- 46004-13 INTERACTION FOR TCDD AND ITS STRUCTURAL ANALOGS--SPECIES COMPARISONS
- 02520-14 TOXIC EFFECTS OF TCDD ON B-CELLS
- 03719-13 CONTROL OF GENE EXPRESSION BY DIOXIN
- 04862-06 EFFECT OF TCDD ON THYMIC LYMPHOCYTE DIFFERENTIATION
- 05673-03 MECHANISM OF TCDD-INDUCED EFFECTS ON CHICK CARDIOGENESIS
- 05677-03 DIFFERENTIAL RESPONSIVENESS TO DIOXIN: ALDH VS. CYP1A1
- 05679-03 DIOXIN ACTION-- NEW PROTEIN PARTNERS FOR THE AH RECEPTOR
- 06439-03 ROLE OF ARNT PROTEIN IN DEVELOPMENT AND CARCINOGENESIS
- 06556-04 BIOMARKERS OF DIOXIN-LIKE COMPOUNDS
- 07009-03 TCDD DEPENDENT REGULATION OF THYMUS DEVELOPMENT
- 07072-03 AH RECEPTOR ASSOCIATED PROTEINS--ROLE IN DIOXIN ACTION
- 07216-03 CONSEQUENCS OF THYMIC ATROPHY INDUCED BY TCDD AND E2
- 02515-16 MOLECULAR TOXICITY OF TCDD
- 05804-01 STUDIES OF PERSONS AT HIGH RISK OF CANCER--PHARMACOGENETIC STUDIES
- 28868-15 CARCINOGEN ACTIVATION AND SCREENING VARIANT CELLS
- MECHANISMS OF THE IMMUNOTOXIC EFFECTS OF HEAVY METALS AND ORGANOCHLORINES
- ESTABLISHMENT OF TOXIC POTENTIAL OF MIXTURES OF ENVIRONMENTALLY RELEVANT CHEMICALS
- 64081-01A1 ALKYL PCDFS--INHIBITION OF MAMMARY CANCER
- ENHANCEMENT OF PRECLINICAL TOXICOLOGY CHARACTERIZATION METHODS TO EVALUATEREPRODUCTIVE HAZARDS IN THE NAVY WORKPLACE.
- DEVELOPMENT OF A COMBINED QSAR AND CLUSTER ANALYSIS BASED RISK ASSESSMENT MODEL.
- THE ROLE OF OXIDATIVE STRESS IN PRODUCING REPRODUCTIVE TOXICITY BY EVALUATIONS INSURROGATE ANIMAL MODELS.
- UTERINE FUNCTION/TOXIC EFFECTS
- THE OTOTOXICITY OF DEVELOPMENTAL EXPOSURE TO POLYCHLORINATED BIPHENYLS
- EFFECTS OF IN UTERO EXPOSURE TO NANOGRAM DOSES OF DIOXIN(2,3,7,8 TETRACHLORODIBENZO-P-DIOXIN) ON MALE AND FEMALE RODENT REPRODUCTIVE DEVELOPMENT: IN VIVO DEVELOPMENTAL EFFECTS OFCHEMICALS THAT BIND AH RECEPTORS.
- CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVEDEVELOPMENT
- The effects of dietary genistein on the growth of chemically-induced mammary tumors in ovariectomized and intact rats
- Endocrine Disruptor Knowledge Base
- VALIDATION OF AN IN VITRO RAT UTERINE ESTROGEN RECEPTOR BINDING ASSAY TO GENERATE RBA DATA FOR USE IN 3D-QSAR MODELING OF POTENTIAL ENDOCRINE DISRUPTORS
- Environmental Toxicology of Halogenated Aromatic Compounds
- Molecular Mechanisms of Action of Halogenated Aromatic Hydrocarbons
- Keratinocyte Culture Model: Toxic Mechanisms
- Regulation of the Ah Receptor Signal Transduction Pathway
- Reproductive and Developmental Toxicity of Dioxin
- Effects of prenatal TCDD exposure on male rat reproductive tract development
- Dioxin and Steroid Regulation in an Endometriosis Model
- Receptor Mediated Developmental Toxicity
- Interaction of PCBs and dioxins with thyroid hormone binding sites
- SAR Approaches to the Developmental Neurotoxicity of PCBs
- Identifying neurotoxic action of endocrine disruptors
- Endometriosis and Exposure to Endocrine Disrupting Compounds
- Interaction of Chemicals and Endocrine Receptors/ Molecular Models
- Development and validation of high through put screening using human cell reporter gene assay.
- Human exposure to xenobiotics with potential endocine effects: evaluation of risks for reproduction and development
- Human exposure to xenobiotics with potential endocrine effects: evaluation of risks for reproduction and development
- Combined effect of representative EDCs in uterotrophic, hershberger and modified one generation assays (contract study)
- Effects of endocrine disrupting chemicals on mouse gonad differentiation, spermgenesis and oogeuesis
- 05352-13 METABOLIC AND PHARMACOLOGICAL DETERMINANTS IN PERINATAL CARCINOGENESIS
- organochlorines and male reproduction
- Steroid hormone metabolism
- Impaired immunity in seals exposed to bioaccumulated environmental contaminants
- Effect of endocrine disruptors on sexual differentiation of the brain in mammals
- Environmental halogenated aromatic hydrocarbons and estrogens; mechanism of action, interactions and test-system development
- Detection of environmental contaminants with estrogenic effects by means of isolated fish hepatocytes
- Review of the evidence for ecological effects of environmental sex hormone disrupters
- Endocrine chemicals in fish and fish cells - strategies for ecotoxicological testing
- Effects of Glucocorticoids on Cytochrome P450 Gene Expression
- Avian Cell Cultures and Embryonic Development
- Examination of white sucker populations for evidence of reproductive and
- Continued studies examining white sucker populations for evidence of recovery
- QSAR, development & application of QSARs
- EFFECT OF ORGANOCHLORINE CONTAMIANTS ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN WILD BIRDS
- EFFECTS OF PCBs ON THE METABOLIC COMPETENCE OF FISH TISSUES
- IDENTIFICATION AND CHARACTERIZATION OF BIOACTIVE LAMPRICIDE FORMULATION COMPONENTS
- DEVELOPMENT AND VALIDATION OF AN AMPHIBIAN MODEL USING XENOPUS LAEVIS
- DEVELOPMENT AND USE OF HEMOPOIETIC CELL CULTURE SYSTEMS FROM FISH, DEVELOPMENT AND APPLICATION OF FISH CELL ASSAYS FOR ASSESSING THE TOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS.
- REPRODUCTIVE EFFECTS OF 2,3,7,8-TCDD ON FRESHWATER FISH AND INVERTEBRATES
- Environmental Endocrine Disruptors' Effect on Reproduction: Hormonal and Cellular Correlates
- Non-lethal monitoring of contaminants in avian and reptilian species
- The Evaluation of Halogenated Aromatic Hydro-Carbons in Fish From the Connecticut River Basin, MA
- Immunological and Reproductive Changes in Chickens Exposed to Dioxin
- Environmental Contaminants, Embryonic Anomalies and Productivity in Migratory Birds
- The Influence of Environmental Estrogens on Carcinogenesis (in trout)
- The Fate and Biolgoical Effects of Xenobiotics in Animals
- INVERTEBRATE MODELS FOR ASSESSING THE DEVELOPMENTAL ANDREPRODUCTIVE EFFECTS OF CONTAMINANTS
- DEVELOPMENT OF SMALL FISH MODELS FOR ASSESSING DEVELOPMENTAL AND REPRODUCTIVE TOXICITY
- Molecular biomarkers of chemical sensitivity in protected species: II. Cell culture bioassays
- AH receptor-mediated developmental toxicity in zebrafish
- TOXICOLOGICAL EVALUATION OF THE REPRODUCTIVE AND IMMUNE SYSTEMS OF THE ST. LAWRENCE RIVER BELUGA WHALES EXPOSED TO ENDOCRINE DISRUPTORS
- Development of Immunochemical Detection Principles for Pesticides and Environmental Hazardous Chemicals
- Environmental Health Impact Assessment in Flanders, Belgium
- Toxic effects of contaminants and adaptive responses of fish and mussels of the upper and median Elbe river
- Identification, exposure assessment and characterization of risks by xenestrogens and other endocrin effective agents present in German freshwater and marine environments: Field and laboratory studies
- Detection and fate of endocrine disruptors in the environment
- Exposure and ecological effects of hazardous substances and drugs in surface waters
- TCDD effects on sex ratio
- Validation of Immunassay Test-Kits for PAHs
- Biochemical response of the mudpuppy (Necturus maculosus) to the pollution of
- Assessment of Trace Organic Contaminants in Sediments and Water from the
- Survey of Contaminants in Suspended Sediments and Water from the Fraser River
- Assessment of Contaminants Associated with Bed Sediments in Canadas Fraser
- 53887-05 MECHANISM OF DIOXIN ACTION
- 07685-03 RECOMBINANT DETECTION SYSTEMS FOR DIOXIN LIKE CHEMICALS
- 05703-08 MOLECULAR CLONING OF AH RECEPTOR POLYMORPHS
- 06011-06 FISH EMBRYONAL STEM CELLS FOR DEVELOPMENT OF TRANSGENICS
- 70714-01 P450 LINK BETWEEN HORMONAL AND CHEMICAL CARCINOGENESIS
- Selected residues determinations within the national residue program
- Dioxins in beef, milk and forage
- Transgenic Biosensors of Environmental Toxicants
- Perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and resistance to Trichinella spiralis infection in rodents
- Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary
- Analyssi of residue levels of endocrine disruptor in human umbilical cords & fetus
- Endocrine disruptors
- Environmental Endocrine Disruption in Avian Wildlife
- Xenoestrogen effects during premeiotic stages of spermatogenesis: Development of an invitro test system and molecular markers of action
- A reporter gene system for detecting and investigating marine pollutants with endocrine disruptive activities
- Identification of the endocgenous ligand for the aryl hydrocarbon receptor
- NATIONAL INVESTIGATION INTO THE OCCURRENCE AND EFFECTS OF ESTROGENIC-ACTIVE COMPOUNDS IN THE AQUATIC ENVIRONMENT
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