EDRI
EDRI
EDRI

Endocrine Disruptor Research
Project Level Inventory
Project Titles




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  • #2 PROJECT TITLE Z01 ES-49010-04 EB TOXICANTS IN HUMAN PLACENTA AND REPRODUCTIVE OUTCOMES IN UKRAINE

  • 00040-33 TOXICOLOGY OF ENVIRONMENTAL CHEMICALS

  • 00184-02 PREDIAGNOSTIC BREAST CANCER SERUM BANK

  • 00834-24 EFFECTS OF CHLORINATED HYDROCARBONS ON MAMMALIAN SYSTEMS

  • 01332-22 REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF DIOXIN

  • 01884-20 HALOGENATED AROMATIC HYDROCARBONS

  • 02515-16 MOLECULAR TOXICITY OF TCDD

  • 02520-14 TOXIC EFFECTS OF TCDD ON B-CELLS

  • 03179-16 IMMUNOTOXICITY OF HEAVY METALS

  • 03230-09 IMMUNE EFFECTS OF METALS--MERCURY-INDUCED AUTOIMMUNE DISEASE

  • 03561-11 DIOXIN/EPITHELIAL CELL INTERACTIONS--MECHANISM AND ASSAY

  • 03606-12 ARACHIDONATE PRODUCTS IN DIOXIN AND PCB TOXICITY

  • 03719-13 CONTROL OF GENE EXPRESSION BY DIOXIN

  • 03749-12 THE EFFECTS OF LEAD ON HYPOTHALAMIC/PITUITARY/GONADAL AXIS

  • 03966-09 CYTOKINE ALTERATIONS IN TCDD IMMUNOTOXICITY

  • 04090-10 CALCIUM-SURROGATE ACTIONS OF LEAD IONS IN SECRETION

  • 04214-11 ENDOCRINE EFFECTS OF REPRODUCTIVE TOXINS IN FEMALE FISH

  • 04244-12 TOXIC CHEMICALS EFFECTS ON FETAL ADRENAL AND LIVER

  • 04411-19 CANCER AND RELATED CONDITIONS IN DOMESTIC ANIMALS--EPIDEMIOLOGIC COMPARISONS

  • 04480-20 STUDIES OF OCCUPATIONAL CANCER

  • 04696-11 EFFECTS-RELATED BIOMARKERS OF TOXIC EXPOSURES

  • 04862-06 EFFECT OF TCDD ON THYMIC LYMPHOCYTE DIFFERENTIATION

  • 04869-10 REGULATION OF THE AH RECEPTOR

  • 04911-09 HEALTH HAZARDS FROM GROUNDWATER CONTAMINATION

  • 04913-08 MULTIDISCIPLINARY STUDY OF POLYCHLORINATED BIPHENYLS (PCBS) AT AKWESASNE

  • 04917-09 PROCEDURES TO ASSESS THE HAZARD OF A SUPERFUND SITE

  • 05033-13 ENVIRONMENTAL/INDUSTRIAL TOXICANTS AND TESTICULAR INJURY

  • 05292-019 BIOKINETICS OF LEAD IN HUMAN PREGNANCY

  • 05352-13 METABOLIC AND PHARMACOLOGICAL DETERMINANTS IN PERINATAL CARCINOGENESIS

  • 05495-06 IMMUNOTOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS

  • 05526-09 ANALYTICAL INVESTIGATIONS OF SELECTED ISSUES IN HUMAN CANCER

  • 05673-03 MECHANISM OF TCDD-INDUCED EFFECTS ON CHICK CARDIOGENESIS

  • 05677-03 DIFFERENTIAL RESPONSIVENESS TO DIOXIN: ALDH VS. CYP1A1

  • 05679-03 DIOXIN ACTION-- NEW PROTEIN PARTNERS FOR THE AH RECEPTOR

  • 05703-08 MOLECULAR CLONING OF AH RECEPTOR POLYMORPHS

  • 05804-01 STUDIES OF PERSONS AT HIGH RISK OF CANCER--PHARMACOGENETIC STUDIES

  • 05903-04 NMDA RECEPTOR AND BEHAVIORAL TOXICITY OF LEAD

  • 05950-06 SUPERFUND BASIC RESEARCH

  • 06011-06 FISH EMBRYONAL STEM CELLS FOR DEVELOPMENT OF TRANSGENICS

  • 06065-05 IMMUNITY IN CHILDREN WITH EXPOSURE TO ENVIRONMENTAL LEAD

  • 06198-05 INTERDISCIPLINARY STUDIES IN REPRODUCTIVE TOXICOLOGY

  • 06263-04 MECHANISM OF PORPHYRIA CAUSED BY TCDD

  • 06265-05 MECHANISMS OF TOXICITY IN TESTES

  • 06272-05 AH RECEPTOR IN NONMAMMALIAN SPECIES

  • 06273-05 MOLECULAR MECHANISMS OF DIOXIN ACTION

  • 06439-03 ROLE OF ARNT PROTEIN IN DEVELOPMENT AND CARCINOGENESIS

  • 06556-04 BIOMARKERS OF DIOXIN-LIKE COMPOUNDS

  • 06587-11 GENE REARRANGEMENTS AS TUMOR SPECIFIC MARKERS

  • 06684-04 LEAD TOXICITY--BIOCHEMICAL AND NEUROENDOCRINE MECHANISMS

  • 06806-03 AH RECEPTOR INDEPENDENT CNS/REPRODUCTIVE EFFECTS OF PCBS

  • 06807-01A1 MOLECULAR BASIS FOR TCDD MODULATION OF ESTROGEN AT OVARY

  • 06811-03 AH RECEPTOR--TRANSGENIC MICE FOR RISK ASSESSMENT

  • 06883-04 TRANSGENIC MODELS OF DIOXIN ACTION

  • 06915-04 LINDANE MODIFICATION OF UTERINE MUSCLE

  • 06995-03 TOXICITY OF ENVIRONMENTAL ESTROGENS

  • 07009-03 TCDD DEPENDENT REGULATION OF THYMUS DEVELOPMENT

  • 07017-03 REGULATION OF GABA EXPRESSION BY NEUROTOXINS

  • 07072-03 AH RECEPTOR ASSOCIATED PROTEINS--ROLE IN DIOXIN ACTION

  • 07084-04 ORGANOCHLORINE RESIDUE LEVELS AND RISK OF BREAST CANCER

  • 07128-03 PESTICIDES AND BREAST CANCER IN NORTH CAROLINA

  • 07216-03 CONSEQUENCS OF THYMIC ATROPHY INDUCED BY TCDD AND E2

  • 07259-04 MAMMARY CELL SIGNALING PRODUCED BY ENVIRONMENTAL AGENTS

  • 07260-04 ORGANOCHLORINE COMPOUNDS AND HUMAN BREAST CYTOCHROME P450

  • 07273-03 TIMING OF ENVIRONMENTAL CHEMICALS IN BREAST CANCER

  • 07375-03 HEALTH EFFECTS OF CHLORINATED COMPOUNDS

  • 07381-03 SUPERFUND BASIC RESEARCH CENTER AT BOSTON UNIVERSITY

  • 07384-03 LEAD AND ORGANOCHLORINES IN NEW YORK CITY

  • 07621-03 VITELLOGENIN AS A BIOMARKER FOR ESTROGENIC XENOBIOTICS

  • 07685-03 RECOMBINANT DETECTION SYSTEMS FOR DIOXIN LIKE CHEMICALS

  • 08030-03 MOLECULAR EPIDEMIOLOGY OF PROSTATE CANCER

  • 1) Investigation of wild populations of fish to determine evidence of endocrine disruption 2) Effects of endocrine disruptors on early life stages of fish 3) Effects of sewage effluents on sex differentiation

  • 1.) Oxytocin: A Neuroendocrine hormone for socio-sexual binding in guinea pigs? 2.) Anogenitale attractivity as an endocrine and social marker in female macaques life?

  • 21009-16 REPRODUCTIVE EFFECTS IN MALES EXPOSED TO ENVIRONMENTAL CHEMICALS

  • 21167-008 DES-EXPOSED COHORT FOLLOWUP

  • 21186-04 LONG TERM EFFECTS OF JUVENILE PESTICIDE EXPOSURE

  • 21197-04 MECHANISTIC STUDIES OF OVARIAN TOXICITY

  • 25001-20 ROLE OF MUTAGENESIS IN CARCINOGENESIS

  • 28868-15 CARCINOGEN ACTIVATION AND SCREENING VARIANT CELLS

  • 33047-007 CANCER AMONG MEN & WOMEN IN AGRICULTURE (SURVEY)

  • 33048-007 CANCER AMONG MEN & WOMEN IN AGRICULTURE

  • 3D-QSAR of EDCs, by computer simulation system using the docking method.

  • 43002-21 HUMAN EXPOSURE TO HALOGENATED AROMATIC COMPOUNDS

  • 44003-20 EPIDEMIOLOGIC STUDY OF REPRODUCTIVE OUTCOMES AND ENVIRONMENTAL EXPOSURES

  • 46004-13 INTERACTION FOR TCDD AND ITS STRUCTURAL ANALOGS--SPECIES COMPARISONS

  • 47002-11 BIOLOGICAL EFFECTS OF PLANT ESTROGENS IN POSTMENOPAUSAL WOMEN

  • 49003-08 ENVIRONMENTAL EFFECTS ON FERTILITY

  • 49005-06 LEAD AND OTHER NEUROTOXINS AS RISK FACTORS FOR AMYOTROPHIC LATERAL SCLEROSIS

  • 49011-04 ADVERSE EFFECTS OF OXIDATIVE STRESS DURING PREGNANCY

  • 50531-000 EXPOSED COHORTS

  • 51017-000 FOLLOW UP OF DES EXPOSED COHORTS

  • 51018-000 FOLLOW UP OF DES EXPOSED COHORTS

  • 51019-000 FOLLOW UP OF DES EXPOSED COHORTS

  • 53887-05 MECHANISM OF DIOXIN ACTION

  • 54349-04 ESTROGENIC PLANT COMPOUNDS AND ETIOLOGY OF BREAST CANCER

  • 58088-04 PERINATAL HORMONAL FACTORS & RAT PROSTATE CARCINOGENESIS

  • 58223-04 SPORE IN BREAST CANCER

  • 59706-02 PANCREATIC CANCER CASE CONTROL STUDY IN SAN FRANCISCO

  • 60698-03 ROLE OF VIP IN ESTROGEN-INDUCED PROLACTINOMAS

  • 60954-03 CASE-CONTROL STUDY OF DMPA AND BREAST CANCER

  • 61093-03 EPIDEMIOLOGY OF EPITHELIAL OVARIAN CANCER

  • 61262-02 METALLOTHIONEIN IN REPRODUCTION AND DEVELOPMENT

  • 61319-02 METALLOTHIONEIN--EFFECTS ON MUTAGENESIS

  • 61668-02 GENISTEIN AND CANCER PREVENTION--MECHANISMS AND MODELS

  • 61742-02 GENISTEIN PROGRAMMING FOR MAMMARY CANCER PREVENTION

  • 61764-03 ANTICARCINOGENIC EFFECTS AND MECHANISMS OF GENISTEIN

  • 62269-01A2 METALLOTHEONEIN AND CADMIUM CARCINOGENESIS IN RAT PROSTATE

  • 62951-03 ENVIRONMENTAL AND GENETIC DETERMINANTS OF BREAST CANCER

  • 62984-03 ENVIRONMENTAL RISK FACTORS AND BREAST CANCER IN THE NHS

  • 62986-03 ORGANOCHLORINE COMPOUNDS AND RISK OF BREAST CANCER

  • 62988-03 ENVIRONMENTAL FACTORS AND BREAST CANCER RISK IN MARYLAND

  • 62991-02 EMF AND BREAST CANCER ON LONG ISLAND

  • 62995-03 ENVIRONMENTAL AND GENETIC DETERMINANTS OF BREAST CANCER

  • 63021-02 EPIDEMIOLOGY OF BREAST CANCER

  • 63550-01A1 NONHODGKINS LYMPHOMA--HAIR DYE AND OTHER EXPOSURES

  • 63748-03 ORAL CONTRACEPTIVES AND OVARIAN CANCER

  • 64081-01A1 ALKYL PCDFS--INHIBITION OF MAMMARY CANCER

  • 66016-01 EFFECTS OF SOY CONSUMPTION ON ESTROGEN IN WOMEN

  • 66201-02 ENVIRONMENT AND BREAST CANCER PROGRAM

  • 66223-02 ENVIRONMENTAL FACTORS INFLUENCING BREAST CANCER

  • 66572-01 BREAST CANCER AND THE ENVIRONMENT ON LONG ISLAND

  • 70060-24 DEVELOPMENTAL BIOLOGY/TOXICOLOGY OF ESTROGENIC ENVIRONMENTAL CHEMICALS

  • 70065-21 CHEMICAL-RECEPTOR INTERACTIONS IN REPRODUCTION AND HORMONAL TOXICITY

  • 70079-03 ESTROGEN RECEPTORS IN MALE REPRODUCTION

  • 70466-01 ESTROGEN EPOXIDATION AND BREAST CANCER

  • 70515-01 ENVIRONMENTAL ESTROGENS AND BREAST CANCER

  • 70536-01 PHYTOESTROGENS AND BREAST CANCER--A PILOT STUDY

  • 70572-01 ESTROGEN/CALCITRIOL IN THE ETIOLOGY OF BREAST CANCER

  • 70655-01 ENVIRONMENTAL CHEMICALS, ESTROGENS, AND BREAST CANCER

  • 70708-01 CADMIUM AND BREAST CANCER ETIOLOGY

  • 70714-01 P450 LINK BETWEEN HORMONAL AND CHEMICAL CARCINOGENESIS

  • A field evaluation of reproductive endocrine alterations in fish exposed to

  • A genotoxicological approach to biomonitoring: biomarkers for carcinogens in bullhead catfish

  • A novel in vivo screening method on ECDs, an application of alpha2u-globulin to EDC screening.

  • A reporter gene system for detecting and investigating marine pollutants with endocrine disruptive activities

  • A short-term in vivo screening system for endocrine disruptors utilizing mosquitofishes (Gambusia affinis and G. holbrooki)

  • A short-term screen for endocrine disruption in juvenile fathead minnows (Pimephales promelas)

  • A study on the development of a new in vitro assay targeted on the possible membrane-receptor mediated EDC effects.

  • A study on the effect of Phthalates on reproduction.

  • A study on the effect of untrauterine exposure on the reproduction of the next generation (F2).

  • A study on the validation of high through put systems using reporter gene assay system and surface plasmon resonance method

  • ADRENAL FUNCTION IN WILDLIFE EXPOSED TO XENOBIOTICS

  • AH receptor-mediated developmental toxicity in zebrafish

  • ANTIBODIES WITH ENDOCRINE ACTIVITY, ALTERNATIVE METHODS TO INCREASE ANIMAL PERFORMANCE

  • ANTIBODY REAGENTS FOR RECEPTOR-BASED BIOSENSORS

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. AN ASSESSMENT OF HUMANPOPULATION AT RISK: THE IMPACT OF CONSUMING CONTAMINATED GREAT LAKES FISH ON NATIVE AMERICANCOMMUNITIES.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. ASSESSING EFFECTS OF HUMANREPRODUCTIVE HEALTH OF PCB EXPOSURE VIA CONSUMPTION OF GREAT LAKES FISH

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. COGNITIVE AND MOTOR EFFECTS OFPCBS EXPOSURE IN OLDER PEOPLE FROM THE MICHIGAN FISHEATER COHORT: EMPHASIS ON THE ROLE OF ORTHO-SUBSTITUTED CONGENERS.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. CONSORTIUM FOR THE HEALTHASSESSMENT OF GREAT LAKES SPORT FISH CONSUMPTION.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. CONTRIBUTION OF NURSING TOBEHAVIORAL CHANGES IN OFFSPRING OF MOTHERS WHO CONSUMED LAKE ONTARIO FISH: TWOMETHODOLOGICAL APPROACHES.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. GREAT LAKES FISH AS A SOURCE OFMATERNAL AND FETAL EXPOSURE TO CHLORINATED HYDROCARBONS.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. HEALTH RISKS FROM CONSUMPTION OFGREAT LAKES FISH

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. MICHIGAN GREAT LAKES HEALTHSTUDIES.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. PCBS AND DDE EXPOSURE AMONGNATIVE AMERICAN MEN FROM CONTAMINATED GREAT LAKES FISH AND WILDLIFE.

  • ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. RESEARCH TITLE: THE NEW YORKSTATE ANGLER COHORT STUDY: EXPOSURE CHARACTERIZATION AND REPRODUCTIVE AND DEVELOPMENTAL EFFECTS.

  • ATSDR LISTING OF HAZARDOUS SUBSTANCES AT SUPERFUND SITES

  • ATSDR MIXTURES RESEARCH INITIATIVE: A RESEARCH PROGRAM ON THE PUBLIC HEALTH ASSESSMENT OFTOXIC INTERACTIONS FOR CHEMICAL MIXTURES.

  • ATSDR MIXTURES RESEARCH INITIATIVE: APPLICATION OF PHYSIOLOGICALLY BASEDPHARMACOKINETIC/PHARMACODYNAMIC (PBPK/PD) MODELING OF CHEMICAL MIXTURES TO HUMAN RISKASSESSMENT.

  • ATSDR MIXTURES RESEARCH INITIATIVE: BINARY WEIGHT-OF-EVIDENCE (BINWOE) DETERMINATIONS FORSELECTED MIXTURES

  • ATSDR MIXTURES RESEARCH INITIATIVE: EVALUATION OF CHEMICAL MIXTURES OF PUBLIC HEALTH CONCERN:ESTIMATION VS EXPERIMENTAL DETERMINATION OF TOXICITY.

  • ATSDR MIXTURES RESEARCH INITIATIVE: FUNCTIONAL TOXICOLOGYTESTING BY THE NATIONAL TOXICOLOGY PROGRAM

  • ATSDR MIXTURES RESEARCH INITIATIVE: LISTING ACTIVITY

  • ATSDR MIXTURES RESEARCH INITIATIVE: TESTING BASIC CONCEPTS AND ASSUMPTIONS IN INTERACTIVETOXICITY.

  • ATSDR TOXICOLOGICAL PROFILES

  • Ah RECEPTOR-MEDIATED ANTI-ESTROGENS, TOXICOLOGICAL ASSESSMENT STRATEGIES FOR COMPLEX MIXTURES, IDENTIFICATION AND ASSESSMENT OF ENVIRONMENTAL ESTROGENS, ESTROGENICITY OF ORGANOCHLORINES, THE ROLE OF ENVIRONMENTAL ESTROGENS IN THE ETIOLOGY OF HUMAN BREAST CANCER

  • Airborne pesticide transport and effects on Sierran ecosystems, CA.

  • Alkylphenols in agricultural ecosystems

  • Amphibians as a model to study endocrine disruptors

  • An Analysis of Maternal Effects in the American Coot: Consequences for Offspring Growth and Survival

  • An extensive research program on the etiology of testicular cancer

  • An in vivo model for detection of reproductive effects of endocrine disruptors

  • Analyses on the effect of ECDs on the estrogen metabolism and possible application to screening.

  • Analysis and Fate of Sewage Derived Organic Contaminants in the Aquatic Environment

  • Analysis of Polyglutamine neurotxicity by endocrine disrupting chemicals a as risk factor

  • Analysis of testis-weight and spermatogenesis in Japanese men by using analytical data of necropsy

  • Analyssi of residue levels of endocrine disruptor in human umbilical cords & fetus

  • Androgen Receptor Expression in Developing Forebrain

  • Androgen Receptors and Hippocampal Function

  • Androgen receptor reporter gene assay system using a human cell line.

  • Animal in vivo studies

  • Annual market basket analysis of the United States Food Supply for pesticides, elemental contaminants and nutrients and industrial contaminants

  • Annual reproductive cycle of largemouth bass and common carp in the Mid-Northeastern Area.

  • Anti-androgenic Pesticides: Impact on Male Reproduction

  • Application in vivo of non-destructive multielement anaylsis method for endocrine disrupting chemicals.

  • Application of Surface Plasmon Resonanse method to high through put screening

  • Application of semipermeable membrane device for monitoring pollution in the Calcasieu River estuarine system

  • Aquatic ecotoxicology

  • Are connexins, the gap junctional integral proteins, involved in male reproductive disorders associated with possible exposure to ED agents ?

  • Aryl hydrocarbons as endocrine disruptors, a method development study.

  • Assessment of Contaminants Associated with Bed Sediments in Canadas Fraser

  • Assessment of Human Risk for Adverse Effects of Endocrine Active Environmental Organohalogen Contaminants

  • Assessment of Trace Organic Contaminants in Sediments and Water from the

  • Assessment of anti-androgen activity in Hershberger assay using indices on cell turnover of prostatic ventral lobe.

  • Assessment of morpho- and histopathological effects of organotin compounds on marine gastropods with special reference to their suitability for a future biological effect monitoring

  • Assessment of reproductive, immunological and (geno)toxic impact of

  • Assessment of the Endocrine Disrupting Potential of Chemicals in Environmental

  • Assessment, management and substitution of hormonally active substances

  • Autonomic innervation of urogenital organs

  • Avian Cell Cultures and Embryonic Development

  • BIOLOGICAL RESPONSES TO PARTICULATE MATERIAL

  • BREAST CANCER AND THE ENVIRONMENT: RISK ASSOCIATED WITH ORGANOCHLORINES

  • Basic studies on the OECD GL407 as an EDC assay

  • Basic study for the assessment of pathological effects of antifouling paints on snails from the German North Sea coast

  • Behavioral Actions of Neuropeptides

  • Behavioral toxicology of PCB's with respect to steroid interactions in rat brain

  • Behavioural effects of environmental pollution on threespine stickleback and guppy

  • Benthic community responses to multiple contaminants

  • Bioaccumulation and effects of PAHs on wildlife

  • Bioaccumulation dynamics of hydrophobic organic contaminants in the Anacostia River food web

  • Bioavailability of colloid-associated metals to estuarine bivalves

  • Biochemical and reproductive effects of gestational/lactational exposure to PCB's with respect to endogenous sex steroids and the proestrogen, methoxychlor

  • Biochemical response of the mudpuppy (Necturus maculosus) to the pollution of

  • Biochemical toxicology of cetaceans

  • Biochemistry and Endocrine Regulation of Aggregation Pheromone Production in Dendroctonus spp. Pine Bark Beetles

  • Biodegradability of ethinylestradiol in activated sludge systems and effects of synthetic androgens and estrogens on freshwater snails

  • Biodegradation of pharmaceuticals and chemicals in the aquatic environment

  • Bioindicators of exposure to and effects of xenoestrogens in the marine environment

  • Biological and molecular aspects of EDCs with a special reference to 3D-QSAR analysis.

  • Biological effects of phytoestrogens in humans

  • Breast Cancer Among Women Exposed to Polychlorinated Biphenyls

  • CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVE DEVELOPMENT: IN VIVO EFFECTS OF ENVIRONMENTAL ESTROGENS

  • CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVEDEVELOPMENT

  • CHAPS-UK: CHemicals And Pregnancy Study - UK

  • CLONING THE NUCLEAR JUVENILE HORMONE RECEPTOR IN LOCUSTA MIGRATORIA

  • COMPARATIVE TOXICOLOGY AND ENDOCRINOLOGY OF AMPHIBIANS

  • COMPARISON OF TWO IN-VITRO AND AN IN-VIVO FISH VITELLOGEN ASSAY.

  • CRADA: 3-D QSAR model to predict in vitro rat uterine estrogen receptor binding

  • CYTOCHROME P450 AND CANCER CHEMOTHERAPY

  • CYTOCHROME P450 TECHNOLOGY FOR ASSESSING THE SAFETY AND EFFICACY OF DBNP.

  • Carcinogenic effect of endocrine disrupting chemicals

  • Central regulation of the hypothalamus-pituitary axis in the female

  • Chemical characterization of the exhaust gases of Bavarian waste incineration plants

  • Chlorinated hydrocarbon contaminants and biological measurement in mink and

  • Chronic toxicity and endocrine effects of di-(2-ethyl hexyl) phthalat on the development of Gammarus (Gammarus fossarum)

  • Collaborative Research: Melanopsin - A Novel Deep Brain Opsin

  • Collection of clinical data about effects of environmental hazards on male and female fertility

  • Combination effects of mixtures of xenoestrogens

  • Combined effect of representative EDCs in uterotrophic, hershberger and modified one generation assays (contract study)

  • Comparative Developmental and Reproductive Toxicity of Endocrine Disrupting Chemicals in an in vivo rat model

  • Comparative analysis of in vitro test systems and in vivo developmental toxicity of pesticides in mammals

  • Concentrations and effects of organotin compounds in the marine environment along the Norwegian coast

  • Concentrations of estrogenously effective/acting substances in the environment

  • Contaminant levels and effects in common snapping turtles and mudpuppies in

  • Contaminants in arctic seaducks

  • Contamination of wetland sediments Indiana Dunes National lakeshore: implications for wetland restoration strategies

  • Continued studies examining white sucker populations for evidence of recovery

  • Courtship Pheromones, Female Receptivity, and Sexual Isolation in Plethodontid Salamanders

  • Critical Stages in Avian Development: Estrogenic Hazards to Altricial and Precocial Birds

  • Critical Stages in Sublethal Exposure to EDCs in a Quail Model System

  • Cross-talk of signal transduction of endocrine disruptors between arylhydrocarbone and steroid hormone receptors

  • Cryptorchidism and xenoestrogens. Is there an assiciation?

  • DETERMINATION OF ANTI-THYROID PROPERTIES OF DIETARY GENISTEIN

  • DETERMINATION OF THE ENDOCRINE DISRUPTEORS, BISPHENOL-A AND NONYL PHENOL, MIGRATING TO FOODS AS THE RESULT OF THEIR USE AS APPROVED INDIRECT ADDITIVE CHEMICALS IN FOOD PACKAGING

  • DEVELOPMENT AND USE OF HEMOPOIETIC CELL CULTURE SYSTEMS FROM FISH, DEVELOPMENT AND APPLICATION OF FISH CELL ASSAYS FOR ASSESSING THE TOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS.

  • DEVELOPMENT AND VALIDATION OF AN AMPHIBIAN MODEL USING XENOPUS LAEVIS

  • DEVELOPMENT OF A BIOASSAY FOR ENVIRONMENTAL ESTROGENS

  • DEVELOPMENT OF A COMBINED QSAR AND CLUSTER ANALYSIS BASED RISK ASSESSMENT MODEL.

  • DEVELOPMENT OF AN IN VIVO ASSAY FOR VITELLOGENIN INDUCTION IN FISH EXPOSED TO SYNTHETIC AND XENOESTROGENS.

  • DEVELOPMENT OF AN IN-VIVO ASSAY FOR INSULIN-LIKE GROWTH FACTOR IN FISH

  • DEVELOPMENT OF SMALL FISH MODELS FOR ASSESSING DEVELOPMENTAL AND REPRODUCTIVE TOXICITY

  • DEVELOPMENTAL NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS

  • DISPOSITION AND PHARMACOKINETICS OF DIOXINS IN PREGNANT AND FETAL RATS.

  • DNA Addutcts of Tamoxifen

  • Defining a Desirable Dietary Fiber Intake

  • Detection and Identification of Estrogenic/Antiestrogenic Compounds in the Marine Environment

  • Detection and Identification of Estrogenic/antiestrogenic Compounds in the Marine Environment

  • Detection and fate of endocrine disruptors in the environment

  • Detection of environmental contaminants with estrogenic effects by means of isolated fish hepatocytes

  • Determination and Screening of Estrogenes, other Pharmaceutics, Antiseptics and Diagnostics in the Aquatic Environment

  • Determination of the effect of Bisphenol-A (BPA) on the life-cycle of the fathead minnow (Pimephales promelas)

  • Determination of the endocrine disruptors dibutylphthalate and butyl benzyl phthlate migrating to foods from food packaging.

  • Determine Isoflavonoid Induction in Legumes and Their Phytoestrogenic Effects in Animal Systems

  • Determine isoflavonoid induction in legumes and their phytoestrogenic effects in animal systems

  • Developement of Immunological method of triazines in environment.

  • Development and testing of in vivo experimentals designs aimed at assessingthe effects (if any) of endocrine-disrupting chemicals on reproduction onfish.

  • Development and validation of a user-friendly, mass-screening assay for aquatic endocrine disruptors

  • Development and validation of high through put screening using human cell reporter gene assay.

  • Development of Crustacean Larvae for In Vivo Screening of Endocrine Disrupting Chemicals in the Marine Environment

  • Development of EDC screening method using cell line transfected with human estrogen receptor gene.

  • Development of Immunochemical Detection Principles for Pesticides and Environmental Hazardous Chemicals

  • Development of Molecular Indicators of Exposure to Pesticides and Endocrine Disrupting Compounds

  • Development of a EDC screening system using sex-differentiation related gene expression in chick embryo

  • Development of a Fish Test to Detect Endocrine Disruptors in Surface Water

  • Development of a PBPK model to predict exposure to xenoestrogens leached from polymeric medical devices

  • Development of a Pharmacokinetic Model for Estradiol in Rats and Humans

  • Development of a bioassay with Marisa cornuarietis (Gastropoda: Prosobranchia) for the assessment of environmental chemicals with hormone-mimetic effects

  • Development of a bioassay with Marisa cornuarietis (Gastropoda:Prosobranchia) for the assessment of environmental chemicals withhormone-mimetic effects

  • Development of a biological indicator of exposure to PAHs in fishes of the Grand Calumet River System

  • Development of a biomarker system for assesment of human exposures to estrogenic substances

  • Development of a high-sensitivity analysis method and its application to monitoring of chemical concentrations in the environment.

  • Development of a marine prophage induction assay for detection of mutagens in seawater samples

  • Development of a new in vitro system for detection of estrogenic activity of environmental chemicals

  • Development of a sensitive assay for androgenic activity using prostate cell lines

  • Development of a vitellogenin assay with fish hepatocytes

  • Development of bioassay system of EDC effects on fish.

  • Development of bioassay system of EDC effects on fish.

  • Development of detection system for endocrine disruptors with special reference to its mechanisms

  • Development of effective bioassay system for endocrine dirsuptors in the workplace.

  • Development of high-sensitivity analysis methods of endocrine disrupting chemicals

  • Development of immunochemical measurement system for triazines in the environment.

  • Development of in vitro human cell culture systems to screen compounds expected to have estrogenic or anti-estrogenic activity.

  • Development of in vitro system exhibiting human metabolic enzyme systems that modify the EDC molecules

  • Development of intrauterine exposure screening rodent model

  • Development of molecular genetics-based bioassays of sediment contaminant effects on benthos

  • Development of screening method of EDCs by the rodent intrauterine exposure models.

  • Development of screening system on the hormone receptor-mediated EDCs by yeast two-hybrid system.

  • Development, characterization, and validation of an in vivo model for evaluating the effects of endocrine disrupting chemicals on sexual differentiation and development in fish.

  • Developmental Effects of Dietary Soy Phytoestrogens

  • Developmental Exposure to Endocrine Disruptors: Fertility and Gene Expression Profiles

  • Developmental effects of endocrine disruptors on mouse reproductive organs

  • Dietary Factors Early in Human Development: Health Consequences of Phytochemical Intake

  • Dietary Fiber, Phytoestrogens, and Reproductive Hormones

  • Dietary Regulations of Sex Hormone Synthesis and Metabolism

  • Differential Expression of Somatostatin Genes in Rainbow Trout

  • Dioxin and Steroid Regulation in an Endometriosis Model

  • Dioxins in beef, milk and forage

  • Dissection of molecular mechanisms underlying the biological effects of endocrine disruptors

  • Do industrial estrogens or their metabolites influence male reproductive function ? A pilot study using mammalian cell lines.

  • Dose-Response Case Studies: Uterine Effects and Switching/Modulation

  • EFFECT OF ORGANOCHLORINE CONTAMIANTS ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN WILD BIRDS

  • EFFECTS OF ENVIRONMENTAL TOXICANTS ON THE STEROID HORMONE PATHWAY

  • EFFECTS OF GESTATIONAL AND/OR LACTATIONAL EXPOSURE TO 2,3,7,8-TCDD ON IMMUNEFUNCTION IN RATS

  • EFFECTS OF IN UTERO EXPOSURE TO NANOGRAM DOSES OF DIOXIN(2,3,7,8 TETRACHLORODIBENZO-P-DIOXIN) ON MALE AND FEMALE RODENT REPRODUCTIVE DEVELOPMENT: IN VIVO DEVELOPMENTAL EFFECTS OFCHEMICALS THAT BIND AH RECEPTORS.

  • EFFECTS OF PCBs ON THE METABOLIC COMPETENCE OF FISH TISSUES

  • EFFECTS OF POLYCHLORINATED BIPHENYLS ON GLUCOCORTICOID RECEPTOR REGULATION.

  • ENDOCRINE CONTROL OF FISH REPRODUCTION, ACTIVIN IN HUMAN PLACENTA

  • ENDOCRINE DISRUPTERS IN VITRO SCREEN

  • ENDOCRINOLOGY OF OSMOREGULATION, GROWTH AND REPRODUCTION IN MOLLUSCS

  • ENDOCRINOLOGY OF THE TESTES, ACTION OF STEROIDS FROM THE TESTES IN EARLY POSTNATAL LIFE AND THEIR SIGNIFICANCE FOR NORMAL DEVELOPMENT, ESTROGENS IN SPERMATOZOA OF THE STALLION

  • ENHANCEMENT OF PRECLINICAL TOXICOLOGY CHARACTERIZATION METHODS TO EVALUATEREPRODUCTIVE HAZARDS IN THE NAVY WORKPLACE.

  • ENVIRONMENTAL EFFECTS OF INDUSTRIAL EFFLUENTS

  • ENVIRONMENTAL FACTORS AFFECTING THYROID FUNCTION IN AQUATIC WILDLIFE

  • ENVIRONMENTAL, HORMONAL, AND METABOLIC CUES IN LAMPREY METAMORPHOSIS

  • ESTABLISHMENT OF AN IN VIVO EMBRYONIC SYSTEM FOR THE ASSESSMENT OF MOLECULAR AND CELLULAR EFFECTS OF ENDOCRINE MODULATION COMPOUNDS

  • ESTABLISHMENT OF TOXIC POTENTIAL OF MIXTURES OF ENVIRONMENTALLY RELEVANT CHEMICALS

  • EVALUATING THE RELATIONSHIP BETWEEN BREAST CANCER

  • EVALUATION OF THE EFFECTS OF ENVIRONMENTAL ESTROGENS ON THE REPRODUCTIVE STATUS OF RAINBOW TROUT

  • EVALUATION OF THE ROLE OF ALTERED ENDOCRINE FUNCTION IN MESOTHELIAL, THYROID AND KIDNEY CANCER INDUCED BY POTASSIUM BROMATE.

  • EVALUATION OF THE ROLE OF ENDOCRINE DISRUPTION IN HEPATOCELLULAR CARCINOGENESIS INDUCED BY DRINKING WATER DISINFECTION BY-PRODUCTS (DBPS).

  • Early Development of the Thymus/Growth Factors and Thyroid Hormones

  • Early life stage exposure to environmental oesrtogens in relation to reproductive and developmental ecology of model and commercially important species

  • Ecological Significance of Heat Shock Proteins as Molecular Chaperones: Temperature Dependence of HSP Biochemical Function in Marine Fish

  • Ecology relevance of hormonally active environmental chemicals in Austria

  • Ecotoxicological relevance of endocrine reactive compounds in the aquatic environment. Investigations along the Elbe River as a model

  • Effect of endocrine disruptors on highly integrated systems.

  • Effect of endocrine disruptors on sexual differentiation of the brain in mammals

  • Effect of isoflavones from Soy and other plants on prevention and development of chronic disease

  • Effect of sewage effluent and estrogen mimics on morphology and behaviour of mosquitofish (Gambusia holbrooki)

  • Effect of sewage effluent and estrogen mimics on morphology and behaviour of mosquitofish (Gambusia holbrooki)

  • Effect of soy protein on blood liids and estrogens

  • Effects by PCBs on neurobehavioral and endocrine measures

  • Effects endocrine disruptors on fish reproduction

  • Effects of Androgen Status on Sperm Maturation

  • Effects of Di-n-butyl phthalate on reproductive development in the rat

  • Effects of EDCs on the uterine carcinogenesis model

  • Effects of Endocrine Disruptors on Mammalian Testis Development

  • Effects of Endocrine-disrupting Contaminants on Flatfish Growth

  • Effects of Glucocorticoids on Cytochrome P450 Gene Expression

  • Effects of Municipal effluents

  • Effects of Oestrogenic Substances in the Aquatic Environment

  • Effects of Organochlorine Contaminants on Avian Endocrine Systems

  • Effects of PCBs on Cognitive Function in Rats

  • Effects of PCBs on reproductive development of mink and otter near Five Island

  • Effects of an endocrine disruptor on prostate development and growth

  • Effects of anthropogenic organochlorines on seabirds

  • Effects of anti-androgen-like chemicals on fetal testicular function and consequences to adults

  • Effects of di-(2ethylhexyl)phtalate (DEHP) on aquatic organisms

  • Effects of early exposure to xenoestrogens on the prostate gland

  • Effects of endocrine disrupting chemicals on central neuronal system and germ cells

  • Effects of endocrine disrupting chemicals on growth of juvenile salmon

  • Effects of endocrine disrupting chemicals on immune system

  • Effects of endocrine disrupting chemicals on immune systems function in estuarine fishes

  • Effects of endocrine disrupting chemicals on mouse gonad differentiation, spermgenesis and oogeuesis

  • Effects of endocrine disrupting chemicals on neuronal stem-cell differentiation

  • Effects of endocrine disrupting chemicals on stress response in flatfish

  • Effects of endocrine disrupting chemicals on the thyroid carcinogenesis.

  • Effects of endocrine disrupting pesticides on birds breeding in orchards in

  • Effects of endocrine disruptors on chemokine production.

  • Effects of endocrine disruptors on fish

  • Effects of endocrine disruptors on fish

  • Effects of endocrine disruptors on mammalian gonads and gametes

  • Effects of endocrine disruptors on marine fish

  • Effects of endocrine disruptors on the reproductive organs and the behaviour of rats

  • Effects of endocrine-disrupting chemicals on reproductive function of fish

  • Effects of environmental contaminants on the response of a suite of biomarkers

  • Effects of environmental endocrine disruptors in the tropical fish, tilapia (oreochromis mossambicus)

  • Effects of environmental endocrine disruptors in the tropical fish, tilapia (oreochromis mossambicus)

  • Effects of environmental estrogens on marine organisms

  • Effects of environmental pollutants on fish reproduction

  • Effects of estrogenic compounds on early development of the chick embryo

  • Effects of estrogens/antiestrogens on receptors and cell proliferation.

  • Effects of fetal and neonatal exposure to EDCs on the structural alterations of Hypothalamic nuclei and the influence on the reproduction.

  • Effects of oestrogen modulators on sex developement of birds

  • Effects of organic contaminants on thyroid functioning of amphibians

  • Effects of prenatal TCDD exposure on male rat reproductive tract development

  • Effects of sewage efflunt discharge on behaviour and reproduction of mosquitofish (Gambusia sp.)

  • Effects on reproductive disorders in fish

  • Elucidation of toxicity mechanisms of endocrine disruptors that bind sex hormone receptors

  • Emulation of sex steroid receptor action in yeast

  • Endocrine Disruption among coastal fish species

  • Endocrine Disruption in Male and Female Fish: The Relationship Between Vitellogenin, Sex Differentiation, and Individual Fitness

  • Endocrine Disruption in Marine Gastropods by Environmental Chemical Mixtures

  • Endocrine Disruption in Marine Invertebrates

  • Endocrine Disruption in the Marine Environment (EDMAR)

  • Endocrine Disruption in the Marine Environment : EDMAR

  • Endocrine Disruptor Knowledge Base

  • Endocrine Disruptors and Host Resistance in Lake Apopka Alligators

  • Endocrine Disruptors and Human Male Reproduction

  • Endocrine Disruptors in German Waterways

  • Endocrine Screening Battery

  • Endocrine active chemicals and sexual differentiation of central nervous system and genital tract organs: Steroid hormone-regulated genes

  • Endocrine chemicals in fish and fish cells - strategies for ecotoxicological testing

  • Endocrine disruption in Pacific Tree Frogs

  • Endocrine disruption in adolescence

  • Endocrine disruption in the estuarine invertebrate Neomysis integer (Crustacea, Mysidacea)

  • Endocrine disruption in the marine environment (EDMAR)

  • Endocrine disruptors

  • Endocrine modulating effects in fish along the Elbe river and in reference areas. Assessment of risks related to the habitat conditions and the naturalvariability of endocrine functions

  • Endocrine modulators and the human female reproductive system

  • Endocrine test development

  • Endocrine-disrupting effects on amphibia

  • Endocrinology of Environmenal Sex Determination in Daphnids

  • Endometriosis and Exposure to Endocrine Disrupting Compounds

  • Energy Balance, Puberty and Foraging Behavior in Naturalistic Conditions

  • Environment and male reproductive health

  • Environment-dependent brain development mediated by hormones andneurotransmitters Environment-dependent brain development mediated by hormones andneurotransmitters Environment-dependent brain development mediated by hormones andneurotransmitters

  • Environmental Chemicals as endocrine disruptors: Amphibians as a model to study the feminization phenomenon

  • Environmental Contaminants, Embryonic Anomalies and Productivity in Migratory Birds

  • Environmental Effects of Industrial Effluents

  • Environmental Endocrine Disruption in Avian Wildlife

  • Environmental Endocrine Disruptors' Effect on Reproduction: Hormonal and Cellular Correlates

  • Environmental Estrogens and the neuroendocrine regulation of reproduction in fish

  • Environmental Exposure Assessment of Endocrine Disrupters in Sewage Treatment Works and River Water

  • Environmental Health Impact Assessment in Flanders, Belgium

  • Environmental Pollutants in aquatic organisms form the San Jose Lagoon

  • Environmental Toxicology of Halogenated Aromatic Compounds

  • Environmental effects on tissues of Baltic seals with special emphasis on organochlorines and uterine leiomyomas

  • Environmental endocrine disruptors: Effects and possible mechanism(s) in young male river otters.

  • Environmental factors and male reproductive functions

  • Environmental factors and male reproductive functions. A cohort study of the incidence of cryptorchidism and hypospadia in 500 newborn boys in the Rotterdam area.

  • Environmental halogenated aromatic hydrocarbons and estrogens; mechanism of action, interactions and test-system development

  • Environmental oestrogens and oestrogenic molecules

  • Environmentally active estrogenes

  • Environmentally-Mediated Endocrine Disruption in Estuarine Crustaceans: A 3-Taxon Multi-Generational Study of Sediment-Associated EDC Effects from the Genetic to Population Levels

  • Epidemiological Study of Testicular Cancer

  • Epidemiological studies of endocrine disrupters and human health

  • Epidemiology of semen quality

  • Establishment and validation of in vitro assays for screening of chemicals with potential estrogenic effects.

  • Establishment of biological methods to monitor endocrine disruptions in aquatic wildlife

  • Estrogen Receptor-Beta Activation of Prolactin Gene Expression

  • Estrogen Receptor-Mediated Endocrine Disruption: Examination of Differences in Species Sensitivities

  • Estrogenic and Toxicological effects of environmental pollutants in Fish

  • Estrogenous effects of xenobiotics: Trial run of an in vitro testsystem for detecting estrogenous effects of xenobiotics with genetically engineered yeast

  • Etilogic factors in breast cancer: estrogenic xenobiotics in fat tissue (a case-control study)

  • Etiologic Factors in Breast Cancer: Estrogenic Xenobiotics in fat tissue (A case control study)

  • Evaluation of Selected Histologic and Immunologic Biomarkers in Fish Collected for the BEST Pilot Program in the Mississippi Drainage

  • Evaluation of endocrine disruption in fish and aquatic invertebrates.

  • Evaluation of the genotoxic potential of genistein in human lymphoblastoid cells

  • Evidence of xenobiotic modulation of reproduction, development, growth,

  • Evironmental halogenated aromatic hydrocarbons, mechanism of action, interactions and test-system development

  • Ex Vivo/In Vitro Testes and Ovary Assay: Evaluation of its Utility to Identify Steroid Biosynthesis Inhibitors

  • Examination of fish exposed to agricultural runoffs for evidence of endocrine

  • Examination of fish for evidence of estrogenic responses downstream of Ontario

  • Examination of the estrogen response pathway in a new vertebrate model

  • Examination of white sucker populations for evidence of reproductive and

  • Exploration of Linkages Among Organochlorines, Oxidative DNA Damage and Breast Cancer

  • Exposure and ecological effects of hazardous substances and drugs in surface waters

  • Exposure and response of Morelet's crocodile (Crocodylus moreletii) populations to endocrine disrupting compounds in Belize, Central America

  • Exposure to endocrine-disruptor chemicals assessed by ligand-receptor interaction analysis of human body fluids

  • FIELD VALIDATION OF VITELLOGENIN INDUCTION IN FERAL MALE FISH AS AN INDICATOR OF EXPOSURE TO ESTROGENIC COMPOUNDS.

  • FISH THYROID FUNCTION

  • FUNCTIONAL TOXICOLOGY TESTING BY THE NATIONAL TOXICOLOGY PROGRAM

  • Fate & effects of reproductive endocrine disruptors in the aquatic environment

  • Female Reproductive Health and Endocrine Disruptors

  • Field study on endocrine disruption and polution-Decline in molluscs

  • Fish cytochrome P450 genes involved in chemical effects

  • Food Toxicology and Safety

  • Food web structure and heavy metal accumulation in a recently established guild of breeding seabirds in southern California

  • Frog Deformities: Role of Endocrine Disruptors During Development

  • Genetic and Molecular Approaches to Signaling by Intracellular Receptors

  • Genetic markers for reproductive toxicology from in vitro mammalian germ cell culture systems

  • Genetic toxicity of estrogenic agents

  • Geographical variation in semen quality

  • HOMOLOGOUS MODELS OF COGNITIVE DEVELOPMENT: EFFECTS OF HYPOTHYROIDISM.

  • HORMONAL CONTROL OF GENE CASCADES IN DROSOPHILA

  • HORMONAL REGULATION OF ADENYLYL CYCLASE IN THE ADRENAL CORTEX, EXPRESSION OF STEROIDOGENIC P450 GENES IN THE ADRENAL CORTEX, DOMAINS OF THE RESPONSE TO CYCLIC AMP IN MOUSE ADRENOCORTICAL TUMOUR CELLS

  • HORMONALLY-MEDIATED ALTERATION OF HEPATIC CYTOCHROME P450 EXPRESSION BY TAMOXIFEN

  • HUMAN HEALTH RISK ASSESSMENT.

  • HYPOTHALAMIC SLICE AS A MODEL FOR TESTING THE EFFECTS OF CHEMICALS.

  • Health assessment in bottlenose dolphins

  • Health of wildlife living in sprayed apple orchards

  • Heavy metal fluxes to the nearshore ocean derived from non-point source pollution in two small estuaries, Oahu, Hawaii

  • Hibernation and the Stress Response

  • Histopathological and morphopathological effects of TOT.

  • Hormonal Control of Pupal Commitment of Metamorphosis

  • Hormonal Control of Reproduction in Cattle, Sheep and Swine

  • Hormone Disruptors in Food

  • Human exposure to phyto- and xenoestrogens using selected chemicals as examples

  • Human exposure to xenobiotics with potential endocine effects: evaluation of risks for reproduction and development

  • Human exposure to xenobiotics with potential endocrine effects: evaluation of risks for reproduction and development

  • Hydroxy-pcbs in blood: identification and effects on thyroid hormone and

  • IDENTIFICATION AND CHARACTERIZATION OF BIOACTIVE LAMPRICIDE FORMULATION COMPONENTS

  • IDENTIFYING THE MODE AND MECHANISM OF ACTION OF ATRAZINE ON ENDOCRINE FUNCTION IN THE FEMALE RAT.

  • IMMUNE ALTERATION ASSOCIATED WITH CHEMICAL EXPOSURE DURING PREGNANCY, AUTOIMMUNITY ASSOCIATED WITH MERCURY EXPOSURE

  • IMMUNOLOGICAL ALTERATIONS BY SFE.

  • IMMUNOTOXICITY OF ORGANOCHLORINE COMPOUNDS IN WILDLIFE SPECIES

  • INVERTEBRATE MODELS FOR ASSESSING THE DEVELOPMENTAL ANDREPRODUCTIVE EFFECTS OF CONTAMINANTS

  • Identification and Characterization of Estrogen Receptor Ligands in Foods

  • Identification and characterization of endocrine activity in vitro and in acute in vivo tests

  • Identification of biomedical endpoints of estrogen action in the male rat with possible confirmation in a primate model and in man

  • Identification of the endocgenous ligand for the aryl hydrocarbon receptor

  • Identification, characterisation and quantification of substances with dioxin-like structure in waste gas condensates of Bavarian waste incineration plants

  • Identification, exposure assessment and characterization of risks by xenestrogens and other endocrin effective agents present in German freshwater and marine environments: Field and laboratory studies

  • Identifying neurotoxic action of endocrine disruptors

  • Immune, Reproductive and Histologic Evaluation in Fish Collected for the Columbia and Rio Grande Basins BEST Program.

  • Immunological and Reproductive Changes in Chickens Exposed to Dioxin

  • Impact of Dietary Intervention on Cardiovascular Disease Risk in Hyperlipidemic Women

  • Impact of contaminants on sexual development and reproduction of amphibians in the Great Lakes Ecosystems

  • Impact of environmental contaminants on an aquatic bird population

  • Impact of exogenous on the expression and function of peroxisome proliferator activated nuclear hormone receptors (PPARs) in femal reproductive cells and stroma

  • Impact of organochlorines on fertility in Greenland

  • Impaired immunity in seals exposed to bioaccumulated environmental contaminants

  • Improve Food Safety Through Discovery and Control of Natural and Induced Toxicants and Antitoxicants

  • In Vitro Methods to Assess Reproductive/Developmental Risk of Environmental Contaminants to Aquatic Organisms

  • In situ monitoring of endocrine disruption using marine fish

  • In situ monitoring of endocrine disruption using marine fish-2

  • In vitro analysis of endocrine activity of environmental samples and of mixtures of chemicals

  • In vivo fish bioassay directed identification of endocrine disrupting chemicals in complex environmental mixtures.

  • Indicators of reproductive status of yellow perch from Lakes Michigan and Mendota.

  • Industrial liability

  • Influence of Plasma Sex Hormone Binding Globulin on the Bioavailability of Phytoestrogens and Xenobiotics

  • Influence of TBT exposure on imposex formation in the common whelk (Buccinum undatum L.)

  • Influence of ecosystems stressed by imissions ...

  • Influence of environmental estrogens on testicular cell function as a possible cause for male fertility disturbances

  • Influence of environmental pollutants on oocyte/embryo development of farm animals

  • Influence of environmental pollutants on physiology of cells of female reproductive tract from farm animals

  • Informatics of the EDCs

  • Integrated Atmospheric Deposition Network

  • Interaction of Chemicals and Endocrine Receptors/ Molecular Models

  • Interaction of PCBs and dioxins with thyroid hormone binding sites

  • Interaction of the Plasma Melatonin Rhythm with other Hormone Rhythms During Development and on Various Light/Dark Cycles

  • Interactions between phytoestrogens and other environmental estrogens with the novel estrogen receptor beta (ERb). Dioxin (Ah receptor)-ERb interactions.

  • Investigating the Spread and Causes of Amphibian Declines in Tropical America

  • Investigation of Biologically Active Compounds in Sewage Sludge and Sludge-Amended Agriculture Soils

  • Investigation of the influence of chlorinated hydrocarbons on the intercellular communication via gap junctions and the regulation thereof by intracellular calcium in cultivated somatic cells of the female reproductive tract of the cow.

  • Investigation of the occurrence and effects of endocrine disrupting substances

  • Investigations of the actual conditions of endocrine disrupting chemicals on testicular function.

  • Isolation and identification of priority substances

  • Juvenoid/Ecdysteroid Interaction on a Cell Line Derived from Moth Imaginal Wing Discs

  • Keratinocyte Culture Model: Toxic Mechanisms

  • LABORATORY ASSESSMENT OF VARIABILITY ASSOCIATED WITH MEASURMENTS OF VITELLOGENIN AND BRAIN AROMATASE ACTIVITY IN FISH3. Project Focus: ECOLOGICAL EFFECTS, EXPOSURE ASSESSMENT

  • LEAD AND CYANIDE AS ENDOCRINE DISRUPTORS OF REPRODUCTION IN RAINBOW TROUT ONCORHYNCHUS MYKISS

  • Larval Transcription Factor Mediating Juvenile Hormone Suppression of Genes

  • Leptin Action on Gonadotropin-Releasing-Hormone Neurons

  • Life-cycle tests with fish

  • Literature Review of the Role of Estrogen in Reproduction and Development of Oviparous Vertebrates

  • Literature Review on Biomarkers for Endocrine Disruption

  • MEASUREMENT OF ESTROGENIC EFFECTS OF MATERIALS ASSOCIATED WITH MEDICAL DEVICES

  • MEASUREMENT OF ESTROGENIC EFFECTS OF MATERIALS ASSOCIATED WITH MEDICAL DEVICES:DEVELOPMENT OF A MOLECULAR ASSAY FOR ESTROGENIC EFFECTS

  • MECHANISMS OF CONTROL OF THE HEPATIC CYTOCHROME P-450 DRUG METABOLISING ENZYMES

  • MECHANISMS OF THE IMMUNOTOXIC EFFECTS OF HEAVY METALS AND ORGANOCHLORINES

  • METABOLIC DISPOSITION OF 1,3,5-TRINITROBENZENE (TNB) ADMINISTERED IN THE DRINKING WATER OF SPRAGUE-DAWLEY RATS.

  • MOLECULAR APPROACHES TO TOXICITY BY TMPP.

  • Market basket analysis of dairy products and commercial fish for dioxins and furans

  • Materials Flow Analysis of major Endocrine Disrupting Industrial Chemicals (Bisphenol A; Dibutylphthalate/Benzylbutylphthalate; Nonylphenol/Alkylphenolethoxylates)

  • Maternal Influences on Hormonal Activity and Behavior

  • Mechanism and biological significance of aneuploidy induction by carcinogenic estrogens and other non-genotoxic carcinogens

  • Mechanism of adverse effects from endocrine disruptors

  • Mechanism of possible human health effect of endocrine disrupting chemicals

  • Mechanisms of Arylhydrocarbon Receptor-Mediated Interactions with Estrogen Receptor in Hypothalamus

  • Mechanistic Assessment of the Masculinization of Neogastropods by Tributyltin

  • Mechanistic studies on the perturbation of organogenesis caused by endocrine disruptors

  • Metabolic Androgenization of Invertebrates by Endocrine-Disrupting Chemicals

  • Methoxychlor and environmental "estrogen" receptors in ERa-minus mice"

  • Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary

  • Molecular Basis of Thyroid in Hormone Action in Brain Development

  • Molecular Genetic Mechanisms of Gonad Development in Zebrafish

  • Molecular Mechanisms and Functional Diversity of the Hemocyanin Gene Family in Cancer magister

  • Molecular Mechanisms of Action of Halogenated Aromatic Hydrocarbons

  • Molecular Mechanisms of Brassinosteroid Action

  • Molecular Mechanisms of Thyroid Hormone Action on Stem Cells

  • Molecular biological approaches for non-destructive assessment of chemical effects on marine mammals

  • Molecular biomarkers of chemical sensitivity in protected species: II. Cell culture bioassays

  • Molecular mechanism of receptor-mediated endocrine disrupting chemicals

  • Multidisciplinary Collaborative Research: Behavioral and Biological Effects of Chronic Social Stress

  • Multidisciplinary Collaborative: Behavioral & Biological Effects of Chronic Social Stress

  • Multidisciplinary Collaborative: Behavioral and Biological Effects of Chronic Social Stress

  • Mutagenic and developmental effects of pesticides and their degradation products in aquatic organisms.

  • NATIONAL INVESTIGATION INTO THE OCCURRENCE AND EFFECTS OF ESTROGENIC-ACTIVE COMPOUNDS IN THE AQUATIC ENVIRONMENT

  • NEUROENDOCRINE PATHWAYS CONTROLLING MALE AND FEMALE REPRODUCTION ASSOCIATEDWITH THE GULF WAR SYNDROME.

  • NO1-ES-55396 THE REPRODUCTIVE OUTCOMES AND ENVIRONMENTAL POLLUTION

  • Neural Control of Adrenocortical Function

  • Neural Substrates for Glucoprivic Regulation of Reproductive Hormone Secretion

  • Neural and Hormonal Substrates of Behavior

  • Neurobiology of Behaviour

  • Neurochemical Correlates of Prolactin Secretion

  • Neuroendocrine Basis of Reproductive Flexibility

  • Neuroendocrine Regulation of a Zinc Finger Protein

  • Neurosteroids: Synthesis and Regulation

  • New Catalysts for the Remediation of Chlorinated Hydrocarbons

  • Non-lethal monitoring of contaminants in avian and reptilian species

  • Nutrition of Herbivores on Rangelands in South Texas as Influenced by Secondary Compounds

  • OCCURRENCE OF AN ENVIRONMENTAL ESTROGEN (4-NONYLPHENOL) IN

  • OECD validation studies

  • OECD validation studies-extended

  • ORGANIZATIONAL AND ACTIVATIONAL INFLUENCES ON COGNITION AND LATERALIZATION

  • OXIDATIVE STRESS IN PRECISION-CUT TISSUE SLICES EXPOSED TO ENDOCRINE DISRUPTORS.

  • Obesity and Reproduction

  • Occurrence of selected endocrine disruptive chemicals and their association with congenital anomalies of the Florida panther.

  • Ocurrence of nonylphenol and nonylphenol polyethoxylates in Canadian aquatic

  • Organization and Development of Circadian Systems

  • PATERNALLY-MEDIATED ADVERSE DRUG EFFECTS ON PROGENY

  • PEROXISOME PROLIFERATION BY DBNP.

  • Parallel Visual and Circadian Pathways to Neuroendocrine Cells

  • Pathogenesis of testicular lesions induced by late gestational exposure to di(n-butyl) phthalate

  • Perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and resistance to Trichinella spiralis infection in rodents

  • Persistent organic pollutants - metabolism and selectively retained metabolites

  • Pesticide Exposure Assessment Study

  • Pharmacokinetics of Di-n-butyl phthalate in pregnant rats

  • Phenolic anthropogenic substances with hormone-like effects: Human toxicology

  • Phthalates in Austrian freshwater fishes

  • Physiological Regulation of proTRH Biosynthesis and Processing

  • Physiological Stress Responses, Aggression and Social Dominance in Wolves

  • Physiological effects of xenobiotic oestrogens in mammals

  • Physiological effects of xenobiotic oestrogens in mammals

  • Phytoestrogen Data for Human Risk Assessment

  • Phytoestrogens and environmental loads

  • Phytoestrogens and prevention of disease

  • Phytoestrogens in Soy-foods

  • Pilot Field Study to Refine the Measurement and Methods of Fifteen Suspect Endocrine Disrupting Compounds in the Neuse River Basin

  • Pilot Study to Evaluate Breast Cancer Risk among Alaska Native Women Potentially Exposed to Environmental Organochlorines

  • Plant uptake of Nonylphenol from sewage sludge amended soils

  • Plasma Vitellogenin Measurements in Fish from the Fraser River Basin

  • Polybrominated diphenyl ethers--an emerging environmental pollutant or an artifact

  • Population Biology of Environmental Gender-Determination in Chrysemys picta

  • Potential effects of hormonally active pesticides on fertility of field hares

  • Pre- and post-conception Exposure to Pesticides and Risk of Adverse Reproductive Outcomes.

  • Prediction In Vitro of the Bioactivity of Potential Xenoestrogens in Animals and Humans

  • Priority Substances and Retinoids in Fish

  • Priority Substances and Thyroid Function in Fish

  • Production of draft OECD Detailed Review Paper on methods to detect sex hormone disrupting activity

  • Production of report of the European Workshop on the Impact of Endocrine Disrupters on Human Health and Wildlife

  • Professional exposure (Greenhouse workers and sprayers) to pesticides

  • Prolactin Secretion in a Teleost Fish: Elucidation of Novel Mechanisms for Rapid Steroid Hormone Action

  • Protective Influence of Melatonin on Proliferation in Breast Cancer Cells

  • Proximate Mechanisms Regulating Fertility

  • Pubertal development of US Boys in NHANES III, 1988-1994

  • Pytoestrogens in the food supply

  • QSAR, development & application of QSARs

  • QSARS FOR THE IDENTIFICATION OF DEVELOPMENTAL AND REPRODUCTIVE TOXICANTS U.S. EPA

  • Quantitative analyses of sexual behaviour as a screening tool of hormone-mimicking effects on animal reproduction

  • REGULATION AND FUNCTION OF OXYGEN RADICALS IN THE CONTROL OF PROGESTERONE SECRETION IN THE RAT CORPUS LUTEUM

  • REGULATION OF EPIDIDYMAL FUNCTION

  • REPRODUCTIVE EFFECTS OF 1,3,5-TRINITROBENZENE (TNB) ADMINISTERED IN THE DRINKINGWATER OF MALE SPRAGUE-DAWLEY RATS.

  • REPRODUCTIVE EFFECTS OF 2,3,7,8-TCDD ON FRESHWATER FISH AND INVERTEBRATES

  • REPRODUCTIVE EFFECTS OF AMMONIUM DINITRAMIDE.

  • REPRODUCTIVE TOXICOLOGY IN TERRESTRIAL MAMMALS OF SIGNIFICANCE TO WESTERN CANADIAN AGRICULTURE

  • ROLE OF ESTROGEN AND RETINOIC ACID IN HUMAN BREAST CANCER CELL GROWTH AND PROGRAMMED CELL DEATH. ROLE OF RETINOIC ACID IN DIFFERENTIATION OF EMBRYONAL CARCINOMA CELLS.

  • Rapid Signaling Pathway for Corticosteriods

  • Receptor Internalization: Endogenous Regulation of Opioid Receptors

  • Receptor Mediated Developmental Toxicity

  • Refinement of Yeast Two-hybrid system on EDC screening

  • Regulated Proopiomelanocortin Expression in the Skin

  • Regulation of Drug and Pesticide Metabolism in Chickens

  • Regulation of the Ah Receptor Signal Transduction Pathway

  • Relational Database of Information in Potential Endocrine Disrupters (REDIPED)

  • Relational Database of Information on Potential Endocrine Disrupters (REDIPED)

  • Release and fate of estrogenic and (anti)androgenic substances into theaquatic environment Release and fate of estrogenic and (anti)androgenic substances into theaquatic environment

  • Release and fate of estrogenic and (anti)androgenic substances to the aquatic environment

  • Reproductive Success of Wading Birds in the Florida Everglades

  • Reproductive and Developmental Toxicity of Dioxin

  • Reproductive and endicrine effects of o,p'-DDT, an environmental estrogen, and p,p'-DDE, and environmental antiandrogen, in male and female atlantic croaker during criticaliod

  • Reproductive effects of organotin compounds and estrogens in marine prosobranch molluscs

  • Research on reproductive biology of wild birds.

  • Research on the effects of EM in aquatic organisms - an assessment of different approaches

  • Response related analytics of environmental compounds with receptor assays

  • Review of phytoestrogens in the human diet

  • Review of the evidence for ecological effects of environmental sex hormone disrupters

  • Role of Clock Proteins PERIOD and TIMELESS on the Activity of the Drosophila Prothoracic Gland

  • Role of Hormones in the Control of Behavior

  • Role of environmental enstrogens/antiestrogens in the development of prostatic discases

  • SAR Approaches to the Developmental Neurotoxicity of PCBs

  • SERUM DIOXIN LEVELS AND SERUM TESTOSTERONE, FSH AND LH LEVELS IN THE AGENT ORANGE VALIDATION STUDY

  • SUBSTANCE-SPECIFIC APPLIED RESEARCH PROGRAM

  • Screening for the presence and effects of endocrine-disrupting chemicals in fish-eating birds of the Lower Rio Grande Valley.

  • Seasonal Plasticity in the GnRH System

  • Seasonal Plasticity in the Nervous System

  • Selected residues determinations within the national residue program

  • Selection and Plasticity in Social Behavior and Signals

  • Serum Follicle-Stimulating Hormone and Luteinizing Hormone Levels in Women Aged 35-60 in the U.S. Population

  • Sex Hormones Effects On The Brain

  • Sex steroid hormone metabolism: enzyme and receptor expression in human tissues

  • Signal Transduction Pathways and Gene Expression in the Circadian Clock System

  • Social Regulation of Reproductive Behavior and Neuroendocrine Processes

  • Soy Protein High & Low in Phytoestrogens & Plasma Lipids in Postmenopausal Females

  • Speciation of metal inputs to coastal waters: consequences for metal transport and bioavailability

  • Species-Specific Endocrine Disruption: PCB- and PAH-Induced Estrogenic Effects

  • Sperm Count Trends in the U.S.

  • Sperm quality studies - Measuring seminiferous tubules

  • Spermiology in the human

  • St.Lawrence River ecosystem monitoring network

  • Steroid concentrations and organochlorine residues in eggs of Common terns.

  • Steroid hormone metabolism

  • Strategies for detection of enviromental endocrine disruptors in animals and in humans.

  • Studies Towards Understanding the Functional Significance of Multiple GnRHs in Vertebrate Brains

  • Studies for elucidating effects of endocrine disruptors on human spermatogenesis

  • Studies of offspring of women occupationally exposed to environmental estrogens

  • Studies on induction mechanism of imposex in gastropods

  • Studies on the EDCs in food containers, elution of the EDCs to the food, and assessment method of food contamination.

  • Studies on the EDCs in food containers, elution of the EDCs to the food, and assessment method of food contamination.

  • Studies on the semen quality in general population of Japan

  • Study of the mechanism of endocrine disruptors on gene expression of C. elegans

  • Study on endocrine disruption in long-lived wildlife

  • Study on endocrine disruption in long-lived wildlife-2

  • Study on endocrine disruption in long-lived wildlife-3

  • Study on endocrine disruption in long-lived wildlife-4

  • Substances with endocrine disrupting potential in various environmental compartments.

  • Survey of Contaminants in Suspended Sediments and Water from the Fraser River

  • TCDD effects on sex ratio

  • THE EFFECTS CADMIUM (CD) AND ITS COMPOUNDS ON PRECISELY TIMED BEHAVIORS IN THERAT.

  • THE EFFECTS OF TCDD ON TRANSGENIC MICE MISSING EITHER THE AH RECEPTOR OR CYP1A2

  • THE EVALUATION OF DBNP FOR ENDOCRINE EFFECTS.

  • THE EVALUATION OF PCBS IN THE MILITARY ENVIRONMENT.

  • THE OTOTOXICITY OF DEVELOPMENTAL EXPOSURE TO POLYCHLORINATED BIPHENYLS

  • THE ROLE OF OXIDATIVE STRESS IN PRODUCING REPRODUCTIVE TOXICITY BY EVALUATIONS INSURROGATE ANIMAL MODELS.

  • TOXIC EFFECTS OF BUTYLATED TRIPHENYL PHOSPHATE-BASED HYDRAULIC FLUID.

  • TOXICANT-INDUCED ALTERATIONS IN OVARIAN MECHANISMS OF OVULATION.

  • TOXICOLOGICAL EVALUATION OF THE REPRODUCTIVE AND IMMUNE SYSTEMS OF THE ST. LAWRENCE RIVER BELUGA WHALES EXPOSED TO ENDOCRINE DISRUPTORS

  • Tanner Stage of Development of US Girls in NHANES III, 1988-1994

  • Temperature Dependent Sex Determination in the Giant River Turtle Podocnemis expansa from Colombian Amazonia

  • Temperature--Not Chromosomes--Determines the Gender of Certain Lower Vertebrates

  • The 4th Copenhagen Workshop on Carcinoma in situ and Testicular Cancer: Molecular and Endocrine aspects.

  • The Effects of Yolk Tetosterone on Nestling Development in the Red-Winged Blackbird

  • The Evaluation of Halogenated Aromatic Hydro-Carbons in Fish From the Connecticut River Basin, MA

  • The Fate and Biolgoical Effects of Xenobiotics in Animals

  • The Influence of Environmental Estrogens on Carcinogenesis (in trout)

  • The Michigan PBB Cohort 20 Years Later: Endocrine Disruption?

  • The Michigan PBB Cohort Twenty Years Later: Endocrine Disruption?

  • The Role of Estrogen Receptor in Aggressive Behavior

  • The Tree Swallow as a bioindicator of riparian wildlife exposure to pulp and

  • The development of an in-vitro assay to determine the influence of biotransformation on the bioaccumulation and genotoxicity of organic compounds in marine top-predators.

  • The ecological viability of constructed wetlands: immune function in birds

  • The effect of endocrine active substances upon soil invertebrates and fresh water fish

  • The effect of oestrogenic compounds on the life history of the pond snail Lymnaea stagnalis

  • The effects of dietary genistein on the growth of chemically-induced mammary tumors in ovariectomized and intact rats

  • The effects of endosulfan, a potential endocrine disrupting chemical in grass shrimp, Palaemonetes pugio

  • The effects of hormones and EDCs on nueronal network

  • The hormonal control and the effects of endocrine-active contaminants on avian secondary sexual characteristics.

  • The influence of environmental oestrogens on vitellogenesis in crustaceans

  • The influence of xenoestrogens on Sertoli-cell number.

  • The mechanisms and effects of endocrine disruption on infertility in the bonnethead shark on Florida's Gulf coast

  • The study on the effects of endocrine disrupting chemicals on steroid hormone receptors

  • Thyroxine and Seasonality in American Tree Sparrows

  • Toxic effects of contaminants and adaptive responses of fish and mussels of the upper and median Elbe river

  • Transgenic Biosensors of Environmental Toxicants

  • Transport and fate of sediment-associated polycyclic aromatic hydrocarbons and trace elements in the Elizabeth River

  • Tree Swallows as bioindicators of riparian willdife exposure to pulp mill

  • Trends in male reproductive anomaly and cancer

  • USE OF THE NAVY NEUROBEHAVIORAL ASSESSMENT BATTERY (NTAB) AS A BEHAVIORALS