Global Endocrine Disruptor Research Project Level Inventory
No experimental endpoint by Focus
Ecological Effects
Biochemistry and Endocrine Regulation of Aggregation Pheromone Production in Dendroctonus spp. Pine Bark Beetles
Bioaccumulation dynamics of hydrophobic organic contaminants in the Anacostia River food web
Fish cytochrome P450 genes involved in chemical effects
Estrogen Receptor-Mediated Endocrine Disruption: Examination of Differences in Species Sensitivities
Literature Review on Biomarkers for Endocrine Disruption
Endocrine modulating effects in fish along the Elbe river and in reference areas. Assessment of risks related to the habitat conditions and the naturalvariability of endocrine functions
Contamination of wetland sediments Indiana Dunes National lakeshore: implications for wetland restoration strategies
Research on reproductive biology of wild birds.
Study on endocrine disruption in long-lived wildlife
Study on endocrine disruption in long-lived wildlife-2
Molecular biomarkers of chemical sensitivity in protected species: II. Cell culture bioassays
Food web structure and heavy metal accumulation in a recently established guild of breeding seabirds in southern California
Heavy metal fluxes to the nearshore ocean derived from non-point source pollution in two small estuaries, Oahu, Hawaii
Informatics of the EDCs
Study on endocrine disruption in long-lived wildlife-3
Study on endocrine disruption in long-lived wildlife-4
Development of bioassay system of EDC effects on fish.
Establishment of biological methods to monitor endocrine disruptions in aquatic wildlife
Chronic toxicity and endocrine effects of di-(2-ethyl hexyl) phthalat on the development of Gammarus (Gammarus fossarum)
Assessment, management and substitution of hormonally active substances
Potential effects of hormonally active pesticides on fertility of field hares
The hormonal control and the effects of endocrine-active contaminants on avian secondary sexual characteristics.
Estrogenous effects of xenobiotics: Trial run of an in vitro testsystem for detecting estrogenous effects of xenobiotics with genetically engineered yeast
Wetland Plants' Roles in Uptake and Transport of Heavy Metals and Remediation
Phytoestrogens in Soy-foods
Phytoestrogens and environmental loads
Physiological effects of xenobiotic oestrogens in mammals
Effects of Oestrogenic Substances in the Aquatic Environment
In Vitro Methods to Assess Reproductive/Developmental Risk of Environmental Contaminants to Aquatic Organisms
EFFECTS OF PCBs ON THE METABOLIC COMPETENCE OF FISH TISSUES
ADRENAL FUNCTION IN WILDLIFE EXPOSED TO XENOBIOTICS
HORMONAL CONTROL OF GENE CASCADES IN DROSOPHILA
DEVELOPMENT OF AN IN-VIVO ASSAY FOR INSULIN-LIKE GROWTH FACTOR IN FISH
COMPARATIVE TOXICOLOGY AND ENDOCRINOLOGY OF AMPHIBIANS
Biochemical toxicology of cetaceans
Exposure Assessment
Molecular biological approaches for non-destructive assessment of chemical effects on marine mammals
Speciation of metal inputs to coastal waters: consequences for metal transport and bioavailability
Application in vivo of non-destructive multielement anaylsis method for endocrine disrupting chemicals.
Studies on the EDCs in food containers, elution of the EDCs to the food, and assessment method of food contamination.
Studies on the EDCs in food containers, elution of the EDCs to the food, and assessment method of food contamination.
04696-11 EFFECTS-RELATED BIOMARKERS OF TOXIC EXPOSURES
Application of semipermeable membrane device for monitoring pollution in the Calcasieu River estuarine system
Investigations of the actual conditions of endocrine disrupting chemicals on testicular function.
Bioavailability of colloid-associated metals to estuarine bivalves
Development of a high-sensitivity analysis method and its application to monitoring of chemical concentrations in the environment.
Development of high-sensitivity analysis methods of endocrine disrupting chemicals
Airborne pesticide transport and effects on Sierran ecosystems, CA.
A reporter gene system for detecting and investigating marine pollutants with endocrine disruptive activities
Identification of the endocgenous ligand for the aryl hydrocarbon receptor
Development and validation of a user-friendly, mass-screening assay for aquatic endocrine disruptors
Transport and fate of sediment-associated polycyclic aromatic hydrocarbons and trace elements in the Elizabeth River
Uptake of anthorpogenic lead and other metals by P Lobata in areas subject to point and non-point pollution stresses around Oahu, Hawaii
Development of a biological indicator of exposure to PAHs in fishes of the Grand Calumet River System
Polybrominated diphenyl ethers--an emerging environmental pollutant or an artifact
Use of a Hybrid Multimedia Compartmental Model to Assist Field Monitoring Project Design for Endocrine Disruptor Detection, Media Concentration, Exposure Model Development and/or Model Confirmation and to Support Fate and Transport Endocrine Disruptor Exposure (EDE) Research
Development of Molecular Indicators of Exposure to Pesticides and Endocrine Disrupting Compounds
Ecology relevance of hormonally active environmental chemicals in Austria
Annual market basket analysis of the United States Food Supply for pesticides, elemental contaminants and nutrients and industrial contaminants
New Catalysts for the Remediation of Chlorinated Hydrocarbons
Persistent organic pollutants - metabolism and selectively retained metabolites
Industrial liability
Pilot Field Study to Refine the Measurement and Methods of Fifteen Suspect Endocrine Disrupting Compounds in the Neuse River Basin
Determination and Screening of Estrogenes, other Pharmaceutics, Antiseptics and Diagnostics in the Aquatic Environment
Human exposure to phyto- and xenoestrogens using selected chemicals as examples
Validation of Immunassay Test-Kits for PAHs
Determination of the endocrine disruptors dibutylphthalate and butyl benzyl phthlate migrating to foods from food packaging.
Development of Immunochemical Detection Principles for Pesticides and Environmental Hazardous Chemicals
biomarkers for estrogen-active compounds
Identification, characterisation and quantification of substances with dioxin-like structure in waste gas condensates of Bavarian waste incineration plants
Selected residues determinations within the national residue program
Pytoestrogens in the food supply
Determine isoflavonoid induction in legumes and their phytoestrogenic effects in animal systems
Market basket analysis of dairy products and commercial fish for dioxins and furans
Dioxins in beef, milk and forage
ANTIBODY REAGENTS FOR RECEPTOR-BASED BIOSENSORS
Phthalates in Austrian freshwater fishes
DETERMINATION OF THE ENDOCRINE DISRUPTEORS, BISPHENOL-A AND NONYL PHENOL, MIGRATING TO FOODS AS THE RESULT OF THEIR USE AS APPROVED INDIRECT ADDITIVE CHEMICALS IN FOOD PACKAGING
Response related analytics of environmental compounds with receptor assays
Substances with endocrine disrupting potential in various environmental compartments.
Endocrine disruptors
Alkylphenols in agricultural ecosystems
Materials Flow Analysis of major Endocrine Disrupting Industrial Chemicals (Bisphenol A; Dibutylphthalate/Benzylbutylphthalate; Nonylphenol/Alkylphenolethoxylates)
Concentrations of estrogenously effective/acting substances in the environment
Development of a new in vitro system for detection of estrogenic activity of environmental chemicals
70536-01 PHYTOESTROGENS AND BREAST CANCER--A PILOT STUDY
05703-08 MOLECULAR CLONING OF AH RECEPTOR POLYMORPHS
ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. PCBS AND DDE EXPOSURE AMONGNATIVE AMERICAN MEN FROM CONTAMINATED GREAT LAKES FISH AND WILDLIFE.
ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. GREAT LAKES FISH AS A SOURCE OFMATERNAL AND FETAL EXPOSURE TO CHLORINATED HYDROCARBONS.
06011-06 FISH EMBRYONAL STEM CELLS FOR DEVELOPMENT OF TRANSGENICS
53887-05 MECHANISM OF DIOXIN ACTION
Juvenoid/Ecdysteroid Interaction on a Cell Line Derived from Moth Imaginal Wing Discs
07685-03 RECOMBINANT DETECTION SYSTEMS FOR DIOXIN LIKE CHEMICALS
ATSDR MIXTURES RESEARCH INITIATIVE: LISTING ACTIVITY
EVALUATION OF THE EFFECTS OF ENVIRONMENTAL ESTROGENS ON THE REPRODUCTIVE STATUS OF RAINBOW TROUT
04917-09 PROCEDURES TO ASSESS THE HAZARD OF A SUPERFUND SITE
ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. MICHIGAN GREAT LAKES HEALTHSTUDIES.
THE EVALUATION OF DBNP FOR ENDOCRINE EFFECTS.
Development of immunochemical measurement system for triazines in the environment.
Developement of Immunological method of triazines in environment.
Dissection of molecular mechanisms underlying the biological effects of endocrine disruptors
Human Health Effects
07259-04 MAMMARY CELL SIGNALING PRODUCED BY ENVIRONMENTAL AGENTS
Androgen Receptor Expression in Developing Forebrain
Development of a Pharmacokinetic Model for Estradiol in Rats and Humans
Impact of organochlorines on fertility in Greenland
Effects by PCBs on neurobehavioral and endocrine measures
CRADA: 3-D QSAR model to predict in vitro rat uterine estrogen receptor binding
Environmentally active estrogenes
Development and validation of high through put screening using human cell reporter gene assay.
VALIDATION OF AN IN VITRO RAT UTERINE ESTROGEN RECEPTOR BINDING ASSAY TO GENERATE RBA DATA FOR USE IN 3D-QSAR MODELING OF POTENTIAL ENDOCRINE DISRUPTORS
Epidemiology of semen quality
Sperm Count Trends in the U.S.
Phytoestrogens and prevention of disease
Effect of isoflavones from Soy and other plants on prevention and development of chronic disease
Establishment and validation of in vitro assays for screening of chemicals with potential estrogenic effects.
OECD validation studies
Production of report of the European Workshop on the Impact of Endocrine Disrupters on Human Health and Wildlife
Etilogic factors in breast cancer: estrogenic xenobiotics in fat tissue (a case-control study)
OECD validation studies-extended
Serum Follicle-Stimulating Hormone and Luteinizing Hormone Levels in Women Aged 35-60 in the U.S. Population
Phytoestrogen Data for Human Risk Assessment
06811-03 AH RECEPTOR--TRANSGENIC MICE FOR RISK ASSESSMENT
06883-04 TRANSGENIC MODELS OF DIOXIN ACTION
FUNCTIONAL TOXICOLOGY TESTING BY THE NATIONAL TOXICOLOGY PROGRAM
Assessment of anti-androgen activity in Hershberger assay using indices on cell turnover of prostatic ventral lobe.
A novel in vivo screening method on ECDs, an application of alpha2u-globulin to EDC screening.
A study on the development of a new in vitro assay targeted on the possible membrane-receptor mediated EDC effects.
Investigation of Biologically Active Compounds in Sewage Sludge and Sludge-Amended Agriculture Soils
Influence of Plasma Sex Hormone Binding Globulin on the Bioavailability of Phytoestrogens and Xenobiotics
06807-01A1 MOLECULAR BASIS FOR TCDD MODULATION OF ESTROGEN AT OVARY
Effect of soy protein on blood liids and estrogens
60698-03 ROLE OF VIP IN ESTROGEN-INDUCED PROLACTINOMAS
HORMONAL REGULATION OF ADENYLYL CYCLASE IN THE ADRENAL CORTEX, EXPRESSION OF STEROIDOGENIC P450 GENES IN THE ADRENAL CORTEX, DOMAINS OF THE RESPONSE TO CYCLIC AMP IN MOUSE ADRENOCORTICAL TUMOUR CELLS
46004-13 INTERACTION FOR TCDD AND ITS STRUCTURAL ANALOGS--SPECIES COMPARISONS
04411-19 CANCER AND RELATED CONDITIONS IN DOMESTIC ANIMALS--EPIDEMIOLOGIC COMPARISONS
04480-20 STUDIES OF OCCUPATIONAL CANCER
ATSDR MIXTURES RESEARCH INITIATIVE: FUNCTIONAL TOXICOLOGYTESTING BY THE NATIONAL TOXICOLOGY PROGRAM
07621-03 VITELLOGENIN AS A BIOMARKER FOR ESTROGENIC XENOBIOTICS
66572-01 BREAST CANCER AND THE ENVIRONMENT ON LONG ISLAND
ATSDR TOXICOLOGICAL PROFILES
SUBSTANCE-SPECIFIC APPLIED RESEARCH PROGRAM
60954-03 CASE-CONTROL STUDY OF DMPA AND BREAST CANCER
05679-03 DIOXIN ACTION-- NEW PROTEIN PARTNERS FOR THE AH RECEPTOR
00184-02 PREDIAGNOSTIC BREAST CANCER SERUM BANK
Prediction In Vitro of the Bioactivity of Potential Xenoestrogens in Animals and Humans
DISPOSITION AND PHARMACOKINETICS OF DIOXINS IN PREGNANT AND FETAL RATS.
ATSDR MIXTURES RESEARCH INITIATIVE: TESTING BASIC CONCEPTS AND ASSUMPTIONS IN INTERACTIVETOXICITY.
ATSDR MIXTURES RESEARCH INITIATIVE: A RESEARCH PROGRAM ON THE PUBLIC HEALTH ASSESSMENT OFTOXIC INTERACTIONS FOR CHEMICAL MIXTURES.
ATSDR MIXTURES RESEARCH INITIATIVE: EVALUATION OF CHEMICAL MIXTURES OF PUBLIC HEALTH CONCERN:ESTIMATION VS EXPERIMENTAL DETERMINATION OF TOXICITY.
06273-05 MOLECULAR MECHANISMS OF DIOXIN ACTION
06065-05 IMMUNITY IN CHILDREN WITH EXPOSURE TO ENVIRONMENTAL LEAD
MEASUREMENT OF ESTROGENIC EFFECTS OF MATERIALS ASSOCIATED WITH MEDICAL DEVICES:DEVELOPMENT OF A MOLECULAR ASSAY FOR ESTROGENIC EFFECTS
01884-20 HALOGENATED AROMATIC HYDROCARBONS
07009-03 TCDD DEPENDENT REGULATION OF THYMUS DEVELOPMENT
07072-03 AH RECEPTOR ASSOCIATED PROTEINS--ROLE IN DIOXIN ACTION
02515-16 MOLECULAR TOXICITY OF TCDD
63550-01A1 NONHODGKINS LYMPHOMA--HAIR DYE AND OTHER EXPOSURES
DEVELOPMENT OF A COMBINED QSAR AND CLUSTER ANALYSIS BASED RISK ASSESSMENT MODEL.
Environmental Pollutants in aquatic organisms form the San Jose Lagoon
DEVELOPMENT OF A BIOASSAY FOR ENVIRONMENTAL ESTROGENS
ATSDR MIXTURES RESEARCH INITIATIVE: APPLICATION OF PHYSIOLOGICALLY BASEDPHARMACOKINETIC/PHARMACODYNAMIC (PBPK/PD) MODELING OF CHEMICAL MIXTURES TO HUMAN RISKASSESSMENT.
03719-13 CONTROL OF GENE EXPRESSION BY DIOXIN
62991-02 EMF AND BREAST CANCER ON LONG ISLAND
05526-09 ANALYTICAL INVESTIGATIONS OF SELECTED ISSUES IN HUMAN CANCER
CYTOCHROME P450 TECHNOLOGY FOR ASSESSING THE SAFETY AND EFFICACY OF DBNP.
PEROXISOME PROLIFERATION BY DBNP.
05677-03 DIFFERENTIAL RESPONSIVENESS TO DIOXIN: ALDH VS. CYP1A1
Combined effect of representative EDCs in uterotrophic, hershberger and modified one generation assays (contract study)
METABOLIC DISPOSITION OF 1,3,5-TRINITROBENZENE (TNB) ADMINISTERED IN THE DRINKING WATER OF SPRAGUE-DAWLEY RATS.
ATSDR MIXTURES RESEARCH INITIATIVE: BINARY WEIGHT-OF-EVIDENCE (BINWOE) DETERMINATIONS FORSELECTED MIXTURES
REPRODUCTIVE EFFECTS OF 1,3,5-TRINITROBENZENE (TNB) ADMINISTERED IN THE DRINKINGWATER OF MALE SPRAGUE-DAWLEY RATS.
OXIDATIVE STRESS IN PRECISION-CUT TISSUE SLICES EXPOSED TO ENDOCRINE DISRUPTORS.
ATSDR GREAT LAKES HUMAN HEALTH EFFECTS RESEARCH PROGRAM. CONSORTIUM FOR THE HEALTHASSESSMENT OF GREAT LAKES SPORT FISH CONSUMPTION.
54349-04 ESTROGENIC PLANT COMPOUNDS AND ETIOLOGY OF BREAST CANCER
Development of in vitro system exhibiting human metabolic enzyme systems that modify the EDC molecules
Development of screening system on the hormone receptor-mediated EDCs by yeast two-hybrid system.
61319-02 METALLOTHIONEIN--EFFECTS ON MUTAGENESIS
MEASUREMENT OF ESTROGENIC EFFECTS OF MATERIALS ASSOCIATED WITH MEDICAL DEVICES
Studies on the semen quality in general population of Japan
Basic studies on the OECD GL407 as an EDC assay
Study of the mechanism of endocrine disruptors on gene expression of C. elegans
3D-QSAR of EDCs, by computer simulation system using the docking method.
Biological and molecular aspects of EDCs with a special reference to 3D-QSAR analysis.
Application of Surface Plasmon Resonanse method to high through put screening
03561-11 DIOXIN/EPITHELIAL CELL INTERACTIONS--MECHANISM AND ASSAY
03606-12 ARACHIDONATE PRODUCTS IN DIOXIN AND PCB TOXICITY
04244-12 TOXIC CHEMICALS EFFECTS ON FETAL ADRENAL AND LIVER
05033-13 ENVIRONMENTAL/INDUSTRIAL TOXICANTS AND TESTICULAR INJURY
05292-019 BIOKINETICS OF LEAD IN HUMAN PREGNANCY
The study on the effects of endocrine disrupting chemicals on steroid hormone receptors
Neural Substrates for Glucoprivic Regulation of Reproductive Hormone Secretion
Development of EDC screening method using cell line transfected with human estrogen receptor gene.
Energy Balance, Puberty and Foraging Behavior in Naturalistic Conditions
Refinement of Yeast Two-hybrid system on EDC screening
Androgen receptor reporter gene assay system using a human cell line.
Sex steroid hormone metabolism: enzyme and receptor expression in human tissues
Development of detection system for endocrine disruptors with special reference to its mechanisms
A study on the validation of high through put systems using reporter gene assay system and surface plasmon resonance method
Molecular mechanism of receptor-mediated endocrine disrupting chemicals
Studies Towards Understanding the Functional Significance of Multiple GnRHs in Vertebrate Brains
Development of bioassay system of EDC effects on fish.
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