1. Sponsor Organization: NIH/NCI

2. Project Title: 51017-000 FOLLOW UP OF DES EXPOSED COHORTS

3. Project Focus:

• Project Primary Focus: Human Health Effects
• Project Secondary Focus:

4. Description:

The primary objective of this contract shall be to provide support services for the Environmental Epidemiology Branch (EEB), Epidemiology & Biostatistics Program (EBP), Division of Cancer Etiology (DCE), National Cancer Institute (NCI), by continuing the follow up of a cohort of DES-exposed individuals for the estimation of long-term cancer risk. In addition, specific sub-studies of non-cancer endpoints, using the resource of the combined cohort., shall be designed and conducted. The recommendations of the 1992 NIH workshop on DES shall be relied upon to form priorities for specific studies. A "Steering Committee" shall be formed to guide and coordinate future research efforts in the DES-exposed and comparison cohorts.

5. References:

6. Inventory Category:

• Primary: Measure
• Secondary:

7. Inventory Subcategory:

• Primary: Exposure Determination
• Secondary:
  • Exposure Follow Up

8. Keywords for Experimental System/Species:

• Species:
  • Human
• Study Type:
  • Field Study
• Fate and Transport:

9. Keywords for Experimental Endpoints:

• Health Effect:
  • Carcinogenesis
• Hormonal Measures:
• Level Of Study:
• Chemistry Metabolism:
  • Exposure Monitoring
• Life Stage:
• Risk Assessment:

10. Chemical Agents:

• Diethylstilbestrol

11. Performing Institution:

• BOSTON UNIVERSITY

12. Contact:

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