1. Sponsor Organization: Ministry of Health & Welfare, Japan

2. Project Title: 3D-QSAR of EDCs, by computer simulation system using the docking method.

3. Project Focus:

• Project Primary Focus: Human Health Effects
• Project Secondary Focus:

4. Description:

The 3D-QSAR using the docking method is performed on the various known EDCs.

5. References:

1. Author: Nishibata Y, Itai A.
   Title: Confirmation of Usefulness of a structure construction program based on three-dimensional receptor structure for rational lead generation.
   Citation: J. Med. Chem. 36: 2921-8
   Year: 1993
   

6. Inventory Category:

• Primary: Models
• Secondary: Methods

7. Inventory Subcategory:

• Primary: Basic Research
• Secondary:
  • Hazard Identification

8. Keywords for Experimental System/Species:

• Species:
• Study Type:
• Fate and Transport:

9. Keywords for Experimental Endpoints:

• Health Effect:
• Hormonal Measures:
• Level Of Study:
• Chemistry Metabolism:
• Life Stage:
• Risk Assessment:

10. Chemical Agents:

• Androgens/Anti-Androgens
• Diethylstilbestrol
• Estrogens/Anti-Estrogens

11. Performing Institution:

• Institute of Medicinal Molecular Design

12. Contact:

• Akiko Itai
  Institute of Medicinal Molecular Design
  Kadokawa Hongo Bld. 4F5-24-5 Hongo, Bunkyo-ku
  Tokyo 113-0033, Japan
  +81-3-5689-4051
  itai@ron.immd.co.jp

Institution: Institute of Medicinal Molecular Design
Division:
Given Name:
Name: Akiko Itai
Title:
Form:
E-Mail: itai@ron.immd.co.jp
Phone: +81-3-5689-4051
Fax:
Street: Kadokawa Hongo Bld. 4F5-24-5 Hongo, Bunkyo-ku
Zip:
City: Tokyo 113-0033, Japan
State:
Country:

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