Research Project Level Inventory by Level of Study Type then Focal Area
Study Types: Biochemistry
Category: Ecological Effects
(70)
Reproductive effects of organotin compounds and estrogens in marine prosobranch molluscs
Steroid hormone metabolism
Vitellogenin assay with fish hepatocytes
Effects of Oestrogenic Substances in the Aquatic Environment
Environmental Chemicals as endocrine disruptors: Amphibians as a model to study the feminization phenomenon
Effect of endocrine disruptors on sexual differentiation of the brain in mammals
Phytoestrogens and environmental loads
Effects of anthropogenic organochlorines on seabirds
Aquatic ecotoxicology
Environmental halogenated aromatic hydrocarbons and estrogens; mechanism of action, interactions and test-system development
Effects of environmental estrogens on marine organisms
Development of a vitellogenin assay with fish hepatocytes
Endocrine-disrupting effects on amphibia
Effects of endocrine disruptors on marine fish
Development of a Fish Test to Detect Endocrine Disruptors in Surface Water
Effects of oestrogen modulators on sex developement of birds
Endocrine chemicals in fish and fish cells - strategies for ecotoxicological testing
Ecotoxicological relevance of endocrine reactive compounds in the aquatic environment. Investigations along the Elbe River as a model
Impact of exogenous on the expression and function of peroxisome proliferator activated nuclear hormone receptors (PPARs) in femal reproductive cells and stroma
Examination of fish for evidence of estrogenic responses downstream of Ontario
Priority Substances and Thyroid Function in Fish
Priority Substances and Retinoids in Fish
Effects of Glucocorticoids on Cytochrome P450 Gene Expression
Avian Cell Cultures and Embryonic Development
Examination of white sucker populations for evidence of reproductive and
Chlorinated hydrocarbon contaminants and biological measurement in mink and
Continued studies examining white sucker populations for evidence of recovery
St.Lawrence River ecosystem monitoring network
Bioaccumulation and effects of PAHs on wildlife
Evidence of xenobiotic modulation of reproduction, development, growth,
Hydroxy-pcbs in blood: identification and effects on thyroid hormone and
Endocrine Disruptors in German Waterways
A field evaluation of reproductive endocrine alterations in fish exposed to
Endocrine test development
Environmental Effects of Industrial Effluents
Life-cycle tests with fish
Effects of Municipal effluents
Fate & effects of reproductive endocrine disruptors in the aquatic environment
ENVIRONMENTAL EFFECTS OF INDUSTRIAL EFFLUENTS
FISH THYROID FUNCTION
EFFECT OF ORGANOCHLORINE CONTAMIANTS ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN WILD BIRDS
DEVELOPMENT AND VALIDATION OF AN AMPHIBIAN MODEL USING XENOPUS LAEVIS
COMPARATIVE TOXICOLOGY AND ENDOCRINOLOGY OF AMPHIBIANS
The Influence of Environmental Estrogens on Carcinogenesis (in trout)
Regulation of Drug and Pesticide Metabolism in Chickens
Critical Stages in Avian Development: Estrogenic Hazards to Altricial and Precocial Birds
Endocrine Disruption among coastal fish species
QSARS FOR THE IDENTIFICATION OF DEVELOPMENTAL AND REPRODUCTIVE TOXICANTS U.S. EPA
DEVELOPMENT OF SMALL FISH MODELS FOR ASSESSING DEVELOPMENTAL AND REPRODUCTIVE TOXICITY
Exposure and response of Morelet's crocodile (Crocodylus moreletii) populations to endocrine disrupting compounds in Belize, Central America
Reproductive and endicrine effects of o,p'-DDT, an environmental estrogen, and p,p'-DDE, and environmental antiandrogen, in male and female atlantic croaker during criticaliod
Metabolic Androgenization of Invertebrates by Endocrine-Disrupting Chemicals
Endocrine Disruption in the Marine Environment (EDMAR)
Development of Crustacean Larvae for In Vivo Screening of Endocrine Disrupting Chemicals in the Marine Environment
Biochemistry and Endocrine Regulation of Aggregation Pheromone Production in Dendroctonus spp. Pine Bark Beetles
Prolactin Secretion in a Teleost Fish: Elucidation of Novel Mechanisms for Rapid Steroid Hormone Action
Identification of biomedical endpoints of estrogen action in the male rat with possible confirmation in a primate model and in man
Effects of endocrine-disrupting chemicals on reproductive function of fish
Effects of endocrine disrupting chemicals on immune systems function in estuarine fishes
Impact of environmental contaminants on an aquatic bird population
Biochemical toxicology of cetaceans
Molecular biomarkers of chemical sensitivity in protected species: II. Cell culture bioassays
AH receptor-mediated developmental toxicity in zebrafish
Impact of contaminants on sexual development and reproduction of amphibians in the Great Lakes Ecosystems
Endocrine Disruption in Marine Gastropods by Environmental Chemical Mixtures
In vitro analysis of endocrine activity of environmental samples and of mixtures of chemicals
Temperature--Not Chromosomes--Determines the Gender of Certain Lower Vertebrates
The effect of endocrine active substances upon soil invertebrates and fresh water fish
TOXICOLOGICAL EVALUATION OF THE REPRODUCTIVE AND IMMUNE SYSTEMS OF THE ST. LAWRENCE RIVER BELUGA WHALES EXPOSED TO ENDOCRINE DISRUPTORS
Category: Exposure Assessment
(53)
Development of Immunochemical Detection Principles for Pesticides and Environmental Hazardous Chemicals
Assessment of morpho- and histopathological effects of organotin compounds on marine gastropods with special reference to their suitability for a future biological effect monitoring
Development of a bioassay with Marisa cornuarietis (Gastropoda: Prosobranchia) for the assessment of environmental chemicals with hormone-mimetic effects
Development of a new in vitro system for detection of estrogenic activity of environmental chemicals
The development of an in-vitro assay to determine the influence of biotransformation on the bioaccumulation and genotoxicity of organic compounds in marine top-predators.
Response related analytics of environmental compounds with receptor assays
Estrogenic and Toxicological effects of environmental pollutants in Fish
Toxic effects of contaminants and adaptive responses of fish and mussels of the upper and median Elbe river
Identification, exposure assessment and characterization of risks by xenestrogens and other endocrin effective agents present in German freshwater and marine environments: Field and laboratory studies
Detection and fate of endocrine disruptors in the environment
Development of a biomarker system for assesment of human exposures to estrogenic substances
biomarkers for estrogen-active compounds
Human exposure to phyto- and xenoestrogens using selected chemicals as examples
Validation of Immunassay Test-Kits for PAHs
Biochemical response of the mudpuppy (Necturus maculosus) to the pollution of
Investigation of the occurrence and effects of endocrine disrupting substances
Assessment of Trace Organic Contaminants in Sediments and Water from the
Plasma Vitellogenin Measurements in Fish from the Fraser River Basin
Survey of Contaminants in Suspended Sediments and Water from the Fraser River
OCCURRENCE OF AN ENVIRONMENTAL ESTROGEN (4-NONYLPHENOL) IN
Assessment of Contaminants Associated with Bed Sediments in Canadas Fraser
Effects of Organochlorine Contaminants on Avian Endocrine Systems
Isolation and identification of priority substances
Effects of environmental contaminants on the response of a suite of biomarkers
Release and fate of estrogenic and (anti)androgenic substances to the aquatic environment
REGULATION OF EPIDIDYMAL FUNCTION
XENOBIOTIC-INDUCED IMPAIRMENT OF THE ENDOCRINE FUNCTION OF TELEOST FISH
THE EVALUATION OF DBNP FOR ENDOCRINE EFFECTS.
ANTIBODY REAGENTS FOR RECEPTOR-BASED BIOSENSORS
Development of in vitro human cell culture systems to screen compounds expected to have estrogenic or anti-estrogenic activity.
Screening for the presence and effects of endocrine-disrupting chemicals in fish-eating birds of the Lower Rio Grande Valley.
Transgenic Biosensors of Environmental Toxicants
Detection and Identification of Estrogenic/antiestrogenic Compounds in the Marine Environment
Examination of the estrogen response pathway in a new vertebrate model
Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary
Release and fate of estrogenic and (anti)androgenic substances into theaquatic environment Release and fate of estrogenic and (anti)androgenic substances into theaquatic environment
Environmental Endocrine Disruption in Avian Wildlife
Xenoestrogen effects during premeiotic stages of spermatogenesis: Development of an invitro test system and molecular markers of action
Amphibians as a model to study endocrine disruptors
Development of a bioassay with Marisa cornuarietis (Gastropoda:Prosobranchia) for the assessment of environmental chemicals withhormone-mimetic effects
Investigating the Spread and Causes of Amphibian Declines in Tropical America
Courtship Pheromones, Female Receptivity, and Sexual Isolation in Plethodontid Salamanders
Early Development of the Thymus/Growth Factors and Thyroid Hormones
A reporter gene system for detecting and investigating marine pollutants with endocrine disruptive activities
Molecular biological approaches for non-destructive assessment of chemical effects on marine mammals
Identification of the endocgenous ligand for the aryl hydrocarbon receptor
NATIONAL INVESTIGATION INTO THE OCCURRENCE AND EFFECTS OF ESTROGENIC-ACTIVE COMPOUNDS IN THE AQUATIC ENVIRONMENT
Early life stage exposure to environmental oesrtogens in relation to reproductive and developmental ecology of model and commercially important species
The influence of environmental oestrogens on vitellogenesis in crustaceans
Effects of endocrine disruptors on fish
Effects of endocrine disruptors on fish
The mechanisms and effects of endocrine disruption on infertility in the bonnethead shark on Florida's Gulf coast
Vitellogenin as a biomarker in screening chemicals for estrogenic effects: Relationship between vitellogenin induction, reproduction and sexual development.
Category: Human Health Effects
(113)
Effects of estrogens/antiestrogens on receptors and cell proliferation.
Emulation of sex steroid receptor action in yeast
Geographical variation in semen quality
Endocrine modulators and the human female reproductive system
Genetic toxicity of estrogenic agents
Phenolic anthropogenic substances with hormone-like effects: Human toxicology
Environment and male reproductive health
Validation of screening methods for estrogenic activity
Establishment and validation of in vitro assays for screening of chemicals with potential estrogenic effects.
Studies of offspring of women occupationally exposed to environmental estrogens
Role of environmental enstrogens/antiestrogens in the development of prostatic discases
Etiologic Factors in Breast Cancer: Estrogenic Xenobiotics in fat tissue (A case control study)
Environmental oestrogens and oestrogenic molecules
Evironmental halogenated aromatic hydrocarbons, mechanism of action, interactions and test-system development
Endocrine Disruptors and Human Male Reproduction
Hormone Disruptors in Food
Mechanism and biological significance of aneuploidy induction by carcinogenic estrogens and other non-genotoxic carcinogens
Interactions between phytoestrogens and other environmental estrogens with the novel estrogen receptor beta (ERb). Dioxin (Ah receptor)-ERb interactions.
Phytoestrogens and prevention of disease
Central regulation of the hypothalamus-pituitary axis in the female
Combination effects of mixtures of xenoestrogens
Influence of environmental estrogens on testicular cell function as a possible cause for male fertility disturbances
00040-33 TOXICOLOGY OF ENVIRONMENTAL CHEMICALS
03179-16 IMMUNOTOXICITY OF HEAVY METALS
66223-02 ENVIRONMENTAL FACTORS INFLUENCING BREAST CANCER
REGULATION AND FUNCTION OF OXYGEN RADICALS IN THE CONTROL OF PROGESTERONE SECRETION IN THE RAT CORPUS LUTEUM
PATERNALLY-MEDIATED ADVERSE DRUG EFFECTS ON PROGENY
ESTABLISHMENT OF TOXIC POTENTIAL OF MIXTURES OF ENVIRONMENTALLY RELEVANT CHEMICALS
70515-01 ENVIRONMENTAL ESTROGENS AND BREAST CANCER
MECHANISMS OF CONTROL OF THE HEPATIC CYTOCHROME P-450 DRUG METABOLISING ENZYMES
ATSDR MIXTURES RESEARCH INITIATIVE: FUNCTIONAL TOXICOLOGYTESTING BY THE NATIONAL TOXICOLOGY PROGRAM
DEVELOPMENT OF A BIOASSAY FOR ENVIRONMENTAL ESTROGENS
ENDOCRINOLOGY OF THE TESTES, ACTION OF STEROIDS FROM THE TESTES IN EARLY POSTNATAL LIFE AND THEIR SIGNIFICANCE FOR NORMAL DEVELOPMENT, ESTROGENS IN SPERMATOZOA OF THE STALLION
ENHANCEMENT OF PRECLINICAL TOXICOLOGY CHARACTERIZATION METHODS TO EVALUATEREPRODUCTIVE HAZARDS IN THE NAVY WORKPLACE.
HORMONAL REGULATION OF ADENYLYL CYCLASE IN THE ADRENAL CORTEX, EXPRESSION OF STEROIDOGENIC P450 GENES IN THE ADRENAL CORTEX, DOMAINS OF THE RESPONSE TO CYCLIC AMP IN MOUSE ADRENOCORTICAL TUMOUR CELLS
Ah RECEPTOR-MEDIATED ANTI-ESTROGENS, TOXICOLOGICAL ASSESSMENT STRATEGIES FOR COMPLEX MIXTURES, IDENTIFICATION AND ASSESSMENT OF ENVIRONMENTAL ESTROGENS, ESTROGENICITY OF ORGANOCHLORINES, THE ROLE OF ENVIRONMENTAL ESTROGENS IN THE ETIOLOGY OF HUMAN BREAST CANCER
HYPOTHALAMIC SLICE AS A MODEL FOR TESTING THE EFFECTS OF CHEMICALS.
THE ROLE OF OXIDATIVE STRESS IN PRODUCING REPRODUCTIVE TOXICITY BY EVALUATIONS INSURROGATE ANIMAL MODELS.
HOMOLOGOUS MODELS OF COGNITIVE DEVELOPMENT: EFFECTS OF HYPOTHYROIDISM.
ENDOCRINE DISRUPTERS IN VITRO SCREEN
CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVEDEVELOPMENT
Protective Influence of Melatonin on Proliferation in Breast Cancer Cells
The effects of dietary genistein on the growth of chemically-induced mammary tumors in ovariectomized and intact rats
DETERMINATION OF ANTI-THYROID PROPERTIES OF DIETARY GENISTEIN
Effect of soy protein on blood liids and estrogens
Effect of isoflavones from Soy and other plants on prevention and development of chronic disease
Effects of early exposure to xenoestrogens on the prostate gland
Determine Isoflavonoid Induction in Legumes and Their Phytoestrogenic Effects in Animal Systems
Food Toxicology and Safety
Keratinocyte Culture Model: Toxic Mechanisms
Biochemical and reproductive effects of gestational/lactational exposure to PCB's with respect to endogenous sex steroids and the proestrogen, methoxychlor
Effects of anti-androgen-like chemicals on fetal testicular function and consequences to adults
Effects of Di-n-butyl phthalate on reproductive development in the rat
DEVELOPMENTAL NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS
EFFECTS OF POLYCHLORINATED BIPHENYLS ON GLUCOCORTICOID RECEPTOR REGULATION.
TOXICANT-INDUCED ALTERATIONS IN OVARIAN MECHANISMS OF OVULATION.
Interaction of PCBs and dioxins with thyroid hormone binding sites
SAR Approaches to the Developmental Neurotoxicity of PCBs
EVALUATION OF THE ROLE OF ALTERED ENDOCRINE FUNCTION IN MESOTHELIAL, THYROID AND KIDNEY CANCER INDUCED BY POTASSIUM BROMATE.
EVALUATION OF THE ROLE OF ENDOCRINE DISRUPTION IN HEPATOCELLULAR CARCINOGENESIS INDUCED BY DRINKING WATER DISINFECTION BY-PRODUCTS (DBPS).
Methoxychlor and environmental "estrogen" receptors in ERa-minus mice"
IDENTIFYING THE MODE AND MECHANISM OF ACTION OF ATRAZINE ON ENDOCRINE FUNCTION IN THE FEMALE RAT.
EFFECTS OF ENVIRONMENTAL TOXICANTS ON THE STEROID HORMONE PATHWAY
Endocrine disruption in the marine environment (EDMAR)
Leptin Action on Gonadotropin-Releasing-Hormone Neurons
Neural Control of Adrenocortical Function
Collaborative Research: Melanopsin - A Novel Deep Brain Opsin
Parallel Visual and Circadian Pathways to Neuroendocrine Cells
Role of Clock Proteins PERIOD and TIMELESS on the Activity of the Drosophila Prothoracic Gland
Neurochemical Correlates of Prolactin Secretion
Hibernation and the Stress Response
Neuroendocrine Regulation of a Zinc Finger Protein
Behavioral Actions of Neuropeptides
Molecular Basis of Thyroid in Hormone Action in Brain Development
Physiological Regulation of proTRH Biosynthesis and Processing
Androgen Receptors and Hippocampal Function
Social Regulation of Reproductive Behavior and Neuroendocrine Processes
Molecular Mechanisms of Thyroid Hormone Action on Stem Cells
Estrogen Receptor-Beta Activation of Prolactin Gene Expression
The Role of Estrogen Receptor in Aggressive Behavior
Receptor Internalization: Endogenous Regulation of Opioid Receptors
Differential Expression of Somatostatin Genes in Rainbow Trout
Interaction of the Plasma Melatonin Rhythm with other Hormone Rhythms During Development and on Various Light/Dark Cycles
Seasonal Plasticity in the Nervous System
Neural Substrates for Glucoprivic Regulation of Reproductive Hormone Secretion
Studies Towards Understanding the Functional Significance of Multiple GnRHs in Vertebrate Brains
Ecological Significance of Heat Shock Proteins as Molecular Chaperones: Temperature Dependence of HSP Biochemical Function in Marine Fish
Rapid Signaling Pathway for Corticosteriods
Androgen Receptor Expression in Developing Forebrain
Regulated Proopiomelanocortin Expression in the Skin
Mechanism of possible human health effect of endocrine disrupting chemicals
Epidemiological studies of endocrine disrupters and human health
Environmental Pollutants in aquatic organisms form the San Jose Lagoon
Developmental Exposure to Endocrine Disruptors: Fertility and Gene Expression Profiles
Endocrine disruption in adolescence
Effects of Endocrine Disruptors on Mammalian Testis Development
Analyses on the effect of ECDs on the estrogen metabolism and possible application to screening.
The study on the effects of endocrine disrupting chemicals on steroid hormone receptors
Molecular mechanism of receptor-mediated endocrine disrupting chemicals
Frog Deformities: Role of Endocrine Disruptors During Development
Identification and characterization of endocrine activity in vitro and in acute in vivo tests
Comparative analysis of in vitro test systems and in vivo developmental toxicity of pesticides in mammals
Human exposure to xenobiotics with potential endocine effects: evaluation of risks for reproduction and development
Human exposure to xenobiotics with potential endocrine effects: evaluation of risks for reproduction and development
Strategies for detection of enviromental endocrine disruptors in animals and in humans.
Endocrine disruption in the estuarine invertebrate Neomysis integer (Crustacea, Mysidacea)
Organization and Development of Circadian Systems
Environmental factors and male reproductive functions. A cohort study of the incidence of cryptorchidism and hypospadia in 500 newborn boys in the Rotterdam area.
CYTOCHROME P450 AND CANCER CHEMOTHERAPY
Professional exposure (Greenhouse workers and sprayers) to pesticides
organochlorines and male reproduction
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