Research Project Level Inventory by Level of Study Type then Focal Area
Study Types: Gene Expression
Category: Ecological Effects(34)- Estrogenous effects of xenobiotics: Trial run of an in vitro testsystem for detecting estrogenous effects of xenobiotics with genetically engineered yeast
- Environmental Chemicals as endocrine disruptors: Amphibians as a model to study the feminization phenomenon
- Aquatic ecotoxicology
- Environmental halogenated aromatic hydrocarbons and estrogens; mechanism of action, interactions and test-system development
- Development of a Fish Test to Detect Endocrine Disruptors in Surface Water
- Detection of environmental contaminants with estrogenic effects by means of isolated fish hepatocytes
- Endocrine chemicals in fish and fish cells - strategies for ecotoxicological testing
- Ecotoxicological relevance of endocrine reactive compounds in the aquatic environment. Investigations along the Elbe River as a model
- Impact of exogenous on the expression and function of peroxisome proliferator activated nuclear hormone receptors (PPARs) in femal reproductive cells and stroma
- Effects of Glucocorticoids on Cytochrome P450 Gene Expression
- Avian Cell Cultures and Embryonic Development
- Assessment of the Endocrine Disrupting Potential of Chemicals in Environmental
- ENVIRONMENTAL EFFECTS OF INDUSTRIAL EFFLUENTS
- ENVIRONMENTAL, HORMONAL, AND METABOLIC CUES IN LAMPREY METAMORPHOSIS
- CLONING THE NUCLEAR JUVENILE HORMONE RECEPTOR IN LOCUSTA MIGRATORIA
- ENDOCRINE CONTROL OF FISH REPRODUCTION, ACTIVIN IN HUMAN PLACENTA
- DEVELOPMENT AND USE OF HEMOPOIETIC CELL CULTURE SYSTEMS FROM FISH, DEVELOPMENT AND APPLICATION OF FISH CELL ASSAYS FOR ASSESSING THE TOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS.
- HORMONAL CONTROL OF GENE CASCADES IN DROSOPHILA
- REPRODUCTIVE EFFECTS OF 2,3,7,8-TCDD ON FRESHWATER FISH AND INVERTEBRATES
- COMPARATIVE TOXICOLOGY AND ENDOCRINOLOGY OF AMPHIBIANS
- The Evaluation of Halogenated Aromatic Hydro-Carbons in Fish From the Connecticut River Basin, MA
- Evaluation of endocrine disruption in fish and aquatic invertebrates.
- QSARS FOR THE IDENTIFICATION OF DEVELOPMENTAL AND REPRODUCTIVE TOXICANTS U.S. EPA
- Reproductive and endicrine effects of o,p'-DDT, an environmental estrogen, and p,p'-DDE, and environmental antiandrogen, in male and female atlantic croaker during criticaliod
- Molecular Mechanisms and Functional Diversity of the Hemocyanin Gene Family in Cancer magister
- Larval Transcription Factor Mediating Juvenile Hormone Suppression of Genes
- Molecular Mechanisms of Brassinosteroid Action
- Fish cytochrome P450 genes involved in chemical effects
- AH receptor-mediated developmental toxicity in zebrafish
- Establishment of biological methods to monitor endocrine disruptions in aquatic wildlife
- In vitro analysis of endocrine activity of environmental samples and of mixtures of chemicals
- Temperature--Not Chromosomes--Determines the Gender of Certain Lower Vertebrates
- TOXICOLOGICAL EVALUATION OF THE REPRODUCTIVE AND IMMUNE SYSTEMS OF THE ST. LAWRENCE RIVER BELUGA WHALES EXPOSED TO ENDOCRINE DISRUPTORS
- Environmentally-Mediated Endocrine Disruption in Estuarine Crustaceans: A 3-Taxon Multi-Generational Study of Sediment-Associated EDC Effects from the Genetic to Population Levels
- Development of a new in vitro system for detection of estrogenic activity of environmental chemicals
- Toxic effects of contaminants and adaptive responses of fish and mussels of the upper and median Elbe river
- Identification, exposure assessment and characterization of risks by xenestrogens and other endocrin effective agents present in German freshwater and marine environments: Field and laboratory studies
- Genetic markers for reproductive toxicology from in vitro mammalian germ cell culture systems
- Biochemical response of the mudpuppy (Necturus maculosus) to the pollution of
- XENOESTROGENIC SCREENING PROCEDURE TO IDENTIFY SUBSTANCES OF CONCERN
- Effects of Organochlorine Contaminants on Avian Endocrine Systems
- Effects of environmental contaminants on the response of a suite of biomarkers
- 53887-05 MECHANISM OF DIOXIN ACTION
- 07685-03 RECOMBINANT DETECTION SYSTEMS FOR DIOXIN LIKE CHEMICALS
- 05703-08 MOLECULAR CLONING OF AH RECEPTOR POLYMORPHS
- REGULATION OF EPIDIDYMAL FUNCTION
- XENOBIOTIC-INDUCED IMPAIRMENT OF THE ENDOCRINE FUNCTION OF TELEOST FISH
- ESTABLISHMENT OF AN IN VIVO EMBRYONIC SYSTEM FOR THE ASSESSMENT OF MOLECULAR AND CELLULAR EFFECTS OF ENDOCRINE MODULATION COMPOUNDS
- Development of in vitro human cell culture systems to screen compounds expected to have estrogenic or anti-estrogenic activity.
- A short-term in vivo screening system for endocrine disruptors utilizing mosquitofishes (Gambusia affinis and G. holbrooki)
- Transgenic Biosensors of Environmental Toxicants
- Development of Molecular Indicators of Exposure to Pesticides and Endocrine Disrupting Compounds
- Examination of the estrogen response pathway in a new vertebrate model
- Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary
- Environmental Endocrine Disruption in Avian Wildlife
- Xenoestrogen effects during premeiotic stages of spermatogenesis: Development of an invitro test system and molecular markers of action
- Amphibians as a model to study endocrine disruptors
- Juvenoid/Ecdysteroid Interaction on a Cell Line Derived from Moth Imaginal Wing Discs
- Development of molecular genetics-based bioassays of sediment contaminant effects on benthos
- A reporter gene system for detecting and investigating marine pollutants with endocrine disruptive activities
- Molecular biological approaches for non-destructive assessment of chemical effects on marine mammals
- Identification of the endocgenous ligand for the aryl hydrocarbon receptor
- NATIONAL INVESTIGATION INTO THE OCCURRENCE AND EFFECTS OF ESTROGENIC-ACTIVE COMPOUNDS IN THE AQUATIC ENVIRONMENT
- Dissection of molecular mechanisms underlying the biological effects of endocrine disruptors
- Hormonal Control of Pupal Commitment of Metamorphosis
- Effects of estrogens/antiestrogens on receptors and cell proliferation.
- Geographical variation in semen quality
- Sex Hormones Effects On The Brain
- Phenolic anthropogenic substances with hormone-like effects: Human toxicology
- Environment and male reproductive health
- Establishment and validation of in vitro assays for screening of chemicals with potential estrogenic effects.
- Role of environmental enstrogens/antiestrogens in the development of prostatic discases
- Environmental oestrogens and oestrogenic molecules
- Assessment of Human Risk for Adverse Effects of Endocrine Active Environmental Organohalogen Contaminants
- Interactions between phytoestrogens and other environmental estrogens with the novel estrogen receptor beta (ERb). Dioxin (Ah receptor)-ERb interactions.
- Combination effects of mixtures of xenoestrogens
- Neurobiology of Behaviour
- 01884-20 HALOGENATED AROMATIC HYDROCARBONS
- 03606-12 ARACHIDONATE PRODUCTS IN DIOXIN AND PCB TOXICITY
- 06273-05 MOLECULAR MECHANISMS OF DIOXIN ACTION
- 46004-13 INTERACTION FOR TCDD AND ITS STRUCTURAL ANALOGS--SPECIES COMPARISONS
- 07009-03 TCDD DEPENDENT REGULATION OF THYMUS DEVELOPMENT
- Z01 ES-23019-01 LMC EFFECTS OF MELATONIN AND ELECTROMAGNETIC FIELDS IN CARCINOGENESIS
- 02515-16 MOLECULAR TOXICITY OF TCDD
- 70655-01 ENVIRONMENTAL CHEMICALS, ESTROGENS, AND BREAST CANCER
- 61262-02 METALLOTHIONEIN IN REPRODUCTION AND DEVELOPMENT
- MECHANISMS OF THE IMMUNOTOXIC EFFECTS OF HEAVY METALS AND ORGANOCHLORINES
- HORMONALLY-MEDIATED ALTERATION OF HEPATIC CYTOCHROME P450 EXPRESSION BY TAMOXIFEN
- ROLE OF ESTROGEN AND RETINOIC ACID IN HUMAN BREAST CANCER CELL GROWTH AND PROGRAMMED CELL DEATH. ROLE OF RETINOIC ACID IN DIFFERENTIATION OF EMBRYONAL CARCINOMA CELLS.
- 61764-03 ANTICARCINOGENIC EFFECTS AND MECHANISMS OF GENISTEIN
- MECHANISMS OF CONTROL OF THE HEPATIC CYTOCHROME P-450 DRUG METABOLISING ENZYMES
- DEVELOPMENT OF A BIOASSAY FOR ENVIRONMENTAL ESTROGENS
- HORMONAL REGULATION OF ADENYLYL CYCLASE IN THE ADRENAL CORTEX, EXPRESSION OF STEROIDOGENIC P450 GENES IN THE ADRENAL CORTEX, DOMAINS OF THE RESPONSE TO CYCLIC AMP IN MOUSE ADRENOCORTICAL TUMOUR CELLS
- Ah RECEPTOR-MEDIATED ANTI-ESTROGENS, TOXICOLOGICAL ASSESSMENT STRATEGIES FOR COMPLEX MIXTURES, IDENTIFICATION AND ASSESSMENT OF ENVIRONMENTAL ESTROGENS, ESTROGENICITY OF ORGANOCHLORINES, THE ROLE OF ENVIRONMENTAL ESTROGENS IN THE ETIOLOGY OF HUMAN BREAST CANCER
- HYPOTHALAMIC SLICE AS A MODEL FOR TESTING THE EFFECTS OF CHEMICALS.
- MEASUREMENT OF ESTROGENIC EFFECTS OF MATERIALS ASSOCIATED WITH MEDICAL DEVICES
- CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVEDEVELOPMENT
- The effects of dietary genistein on the growth of chemically-induced mammary tumors in ovariectomized and intact rats
- Endocrine Disruptor Knowledge Base
- Effects of early exposure to xenoestrogens on the prostate gland
- Determine Isoflavonoid Induction in Legumes and Their Phytoestrogenic Effects in Animal Systems
- Environmental Toxicology of Halogenated Aromatic Compounds
- Molecular Mechanisms of Action of Halogenated Aromatic Hydrocarbons
- Keratinocyte Culture Model: Toxic Mechanisms
- Regulation of the Ah Receptor Signal Transduction Pathway
- Exploration of Linkages Among Organochlorines, Oxidative DNA Damage and Breast Cancer
- Effects of prenatal TCDD exposure on male rat reproductive tract development
- Dioxin and Steroid Regulation in an Endometriosis Model
- Receptor Mediated Developmental Toxicity
- Effects of anti-androgen-like chemicals on fetal testicular function and consequences to adults
- Effects of Di-n-butyl phthalate on reproductive development in the rat
- Pathogenesis of testicular lesions induced by late gestational exposure to di(n-butyl) phthalate
- EFFECTS OF POLYCHLORINATED BIPHENYLS ON GLUCOCORTICOID RECEPTOR REGULATION.
- EVALUATION OF THE ROLE OF ALTERED ENDOCRINE FUNCTION IN MESOTHELIAL, THYROID AND KIDNEY CANCER INDUCED BY POTASSIUM BROMATE.
- EVALUATION OF THE ROLE OF ENDOCRINE DISRUPTION IN HEPATOCELLULAR CARCINOGENESIS INDUCED BY DRINKING WATER DISINFECTION BY-PRODUCTS (DBPS).
- Methoxychlor and environmental "estrogen" receptors in ERa-minus mice"
- IDENTIFYING THE MODE AND MECHANISM OF ACTION OF ATRAZINE ON ENDOCRINE FUNCTION IN THE FEMALE RAT.
- Species-Specific Endocrine Disruption: PCB- and PAH-Induced Estrogenic Effects
- Mechanisms of Arylhydrocarbon Receptor-Mediated Interactions with Estrogen Receptor in Hypothalamus
- Molecular Genetic Mechanisms of Gonad Development in Zebrafish
- Leptin Action on Gonadotropin-Releasing-Hormone Neurons
- Neural Control of Adrenocortical Function
- Collaborative Research: Melanopsin - A Novel Deep Brain Opsin
- Role of Clock Proteins PERIOD and TIMELESS on the Activity of the Drosophila Prothoracic Gland
- Signal Transduction Pathways and Gene Expression in the Circadian Clock System
- Genetic and Molecular Approaches to Signaling by Intracellular Receptors
- Role of Hormones in the Control of Behavior
- Hibernation and the Stress Response
- Neuroendocrine Regulation of a Zinc Finger Protein
- Behavioral Actions of Neuropeptides
- Molecular Basis of Thyroid in Hormone Action in Brain Development
- Molecular Mechanisms of Thyroid Hormone Action on Stem Cells
- Estrogen Receptor-Beta Activation of Prolactin Gene Expression
- The Role of Estrogen Receptor in Aggressive Behavior
- Differential Expression of Somatostatin Genes in Rainbow Trout
- Studies Towards Understanding the Functional Significance of Multiple GnRHs in Vertebrate Brains
- Androgen Receptor Expression in Developing Forebrain
- Are connexins, the gap junctional integral proteins, involved in male reproductive disorders associated with possible exposure to ED agents ?
- Mechanism of possible human health effect of endocrine disrupting chemicals
- Effect of endocrine disruptors on highly integrated systems.
- Epidemiological studies of endocrine disrupters and human health
- Effects of an endocrine disruptor on prostate development and growth
- Developmental Exposure to Endocrine Disruptors: Fertility and Gene Expression Profiles
- Effects of Endocrine Disruptors on Mammalian Testis Development
- Analysis of Polyglutamine neurotxicity by endocrine disrupting chemicals a as risk factor
- Effects of endocrine disrupting chemicals on neuronal stem-cell differentiation
- The study on the effects of endocrine disrupting chemicals on steroid hormone receptors
- Sex steroid hormone metabolism: enzyme and receptor expression in human tissues
- Biological and molecular aspects of EDCs with a special reference to 3D-QSAR analysis.
- A novel in vivo screening method on ECDs, an application of alpha2u-globulin to EDC screening.
- Development of screening system on the hormone receptor-mediated EDCs by yeast two-hybrid system.
- Developmental effects of endocrine disruptors on mouse reproductive organs
- Study of the mechanism of endocrine disruptors on gene expression of C. elegans
- Effects of endocrine disruptors on chemokine production.
- Cross-talk of signal transduction of endocrine disruptors between arylhydrocarbone and steroid hormone receptors
- Development of a EDC screening system using sex-differentiation related gene expression in chick embryo
- The effects of hormones and EDCs on nueronal network
- Mechanistic studies on the perturbation of organogenesis caused by endocrine disruptors
- Frog Deformities: Role of Endocrine Disruptors During Development
- Identification and characterization of endocrine activity in vitro and in acute in vivo tests
- Endocrine active chemicals and sexual differentiation of central nervous system and genital tract organs: Steroid hormone-regulated genes
- Comparative analysis of in vitro test systems and in vivo developmental toxicity of pesticides in mammals
- Human exposure to xenobiotics with potential endocrine effects: evaluation of risks for reproduction and development
- Strategies for detection of enviromental endocrine disruptors in animals and in humans.
- CYTOCHROME P450 AND CANCER CHEMOTHERAPY
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